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Table 2 HRs (95%CIs) for mortality according to serum 25 (OH)D concentrations among hypertensive participants

From: Association between serum 25-hydroxyvitamin D and vitamin D dietary supplementation and risk of all-cause and cardiovascular mortality among adults with hypertension

 

Serum 25 (OH)D concentrations (nmol/L)

≥75.0

50.0-74.9

25.0-49.9

<25.0

P for trend

All-cause mortality

     

Deaths, yes (%) (all = 4481)

1462/6796 (21.51)

1645/6993 (23.52)

1192/4993 (23.87)

182/718 (25.35)

 

Model 1 HR (95% CI) P-value

1.00

1.00 (0.91–1.09) 0.91

1.20 (1.05–1.36) 0.01

1.73 (1.40–2.13) < 0.001

< 0.001

Model 2 HR (95% CI) P-value

1.00

1.19 (1.09–1.30) < 0.001

1.79 (1.59–2.02) < 0.001

3.04 (2.44–3.79) < 0.001

< 0.001

Model 3 HR (95% CI) P-value

1.00

1.17 (0.95–1.45) 0.14

1.71 (1.22–2.40) 0.002

1.97 (1.15–3.39) 0.01

< 0.001

CVD mortality

     

Deaths, yes (%) (all = 1940)

655/6796 (9.64)

686/6993 (9.81)

521/4993 (10.43)

78/718 (10.86)

 

Model 1 HR (95% CI) P-value

1.00

0.96 (0.84–1.10) 0.56

1.24 (1.04–1.49) 0.02

1.65 (1.21–2.25) 0.002

0.01

Model 2 HR (95% CI) P-value

1.00

1.15 (1.01–1.32) 0.04

1.87 (1.55–2.27) < 0.001

2.91 (2.04–4.13) < 0.001

< 0.001

Model 3 HR (95% CI) P-value

1.00

1.06 (0.75–1.49) 0.75

1.71 (0.94–3.14) 0.08

1.42 (0.70–2.91) 0.33

0.12

  1. Abbreviations: CVD, cardiovascular disease
  2. Model 1: Unadjusted; Model 2: Adjusted for age, sex, race and survey cycle; Model 3: Adjusted for age, gender, race, survey cycle, education, PIR, BMI, smoking, drinking, during of hypertension, antihypertensive therapy, vitamin D supplementation and co-morbidities