Table 1 Clinical characteristics of the study population according to obese and NAFLD categories
Variables | Overall (n = 2538) | Lean participants | Obese participants | ||||
|---|---|---|---|---|---|---|---|
NAFLD (n = 163) | Without NAFLD (n = 1081) | P value | NAFLD (n = 690) | Without NAFLD (n = 604) | P value | ||
Age (year) | 54.08 (6.85) | 54.84 (6.59) | 53.81 (6.96) | 0.078 | 54.23 (6.60) | 54.18 (6.99) | 0.901 |
Male gender (%) | 1360 (53.39) | 86 (52.76) | 430 (39.78) | 0.002 | 485 (70.29) | 359 (59.44) | < 0.001 |
Body mass index (kg/m2) | 24.22 (2.96) | 22.77 (1.14) | 21.71 (1.54) | < 0.001 | 27.09 (2.18) | 25.83 (1.73) | < 0.001 |
Waist circumference (cm) | 85.13 (8.67) | 83.34 (5.12) | 78.66 (6.12) | < 0.001 | 92.88 (6.39) | 88.35 (6.37) | < 0.001 |
Systolic blood pressure (mmHg) | 127.93 (18.38) | 127.64 (16.86) | 122.77 (18.51) | 0.002 | 134.37 (17.41) | 129.88 (16.89) | < 0.001 |
Diastolic blood pressure (mmHg) | 78.37 (11.56) | 78.08 (9.98) | 74.77 (11.26) | < 0.001 | 82.96 (10.72) | 79.65 (11.34) | < 0.001 |
Alanine aminotransferase (U/L) | 23.21 (19.06) | 28.64 (45.74) | 18.24 (12.69) | 0.004 | 30.78 (16.61) | 22.00 (15.60) | < 0.001 |
γ-Glutamyl Transpeptidase (U/L) | 29.90 (31.84) | 35.50 (35.39) | 23.00 (31.34) | < 0.001 | 40.49 (32.64) | 28.64 (26.98) | < 0.001 |
Triglyceride (mmol/L) | 1.63 (1.14) | 2.02 (1.16) | 1.26 (0.82) | < 0.001 | 2.17 (1.43) | 1.54 (0.95) | < 0.001 |
HDL-cholesterol (mmol/L) | 1.22 (0.34) | 1.12 (0.26) | 1.36 (0.36) | < 0.001 | 1.04 (0.25) | 1.19 (0.28) | < 0.001 |
LDL-cholesterol (mmol/L) | 2.75 (0.72) | 2.83 (0.79) | 2.69 (0.68) | 0.016 | 2.79 (0.75) | 2.79 (0.74) | 0.839 |
Serum uric acid (μmol/L) | 325.71 (81.72) | 332.94 (73.72) | 293.72 (71.12) | < 0.001 | 369.41 (78.22) | 331.10 (80.78) | < 0.001 |
Fasting blood glucose (mmol/L) | 5.21 (1.21) | 5.53 (1.34) | 4.99 (1.03) | < 0.001 | 5.57 (1.50) | 5.12 (0.94) | < 0.001 |
Vitamin D (nmol/L) | 61.21 (21.64) | 60.95 (18.54) | 61.32 (22.97) | 0.844 | 59.03 (19.46) | 63.56 (22.09) | < 0.001 |