Skip to main content

Table 3 Systematic reviews on Vitamin D for prevention or treatment (in chronological order)

From: Vitamin D in health and disease: Current perspectives

Area Number
of studies
Type Doses Conclusion Reference
Cardiovascular events 17 Prospective ~1000IU S not SS 162
Cardiometabolic outcomes 31 Observ/Trial Range No effect 163
Fracture prevention 7 Randomised 10-20 mcg
+ Ca
No effect
Reduced risk
164
164
Physical performance 8
8
Observational
Intervention
-
-
Positive (5/8)
Mixed
165
165
Kidney disease
(-dialysis)
16 RCT - Uncertain 166
Kidney disease (+dialysis) 60 RCT - Uncertain 167
Cystic fibrosis 3 (q)RCT 800-1600IU No effect 168
Risk of falling 8 RCT 700-1000IU
200-600IU
Reduced risk
No effect
169
169
Hypertension 11 RCT - S - SS 170
Risk of falling 111* RT or interv. - No effect 171
Fracture prevention 45 (q)RCT -
+Ca
No effect
S not SS
172
172
Risk of Type 1 diabetes 5 Observational - Uncertain 136
Parathyroid hormone 52 Intervention _ Decrease 173
Mortality 18 RCT 2300-2000IU Uncertain 174
Risk of fall/fracture 9 - - Decrease (trend) 175
Risk of fracture 12 RCT 700-800IU
400IU
Decrease (trend)
No effect
176
176
Risk of fall 10 RCT - Decrease 177
Bone density Fracture 17
17
RCT
RCT
-
-
Uncertain
Reduction
178
  1. S not SS: Small effect - not statistically significant (sub-groups are discounted); RCT: Randomised controlled trial {(q) - quasi}; * Multiple factor study.