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Table 3 The difference (95% CIs) in annual changes in total gray matter and total white matter (%) across the three dietary patterns, in men and women (n = 1636) a, b

From: Associations of dietary patterns and longitudinal brain-volume change in Japanese community-dwelling adults: results from the national institute for longevity sciences-longitudinal study of aging

 

Total gray matter

Total white matter

β (95% CI)

P-value

β (95% CI)

P-value

Men (n =815)

 Model 1 c

  Estimate (SE) of Intercept

0.141 (0.457)

 

-0.931 (0.402)

 

  Vegetable-Fruit-Dairy diet

-0.112 (-0.290 to 0.067)

0.221

0.005 (-0.152 to 0.162)

0.953

  Traditional Japanese diet

-0.098 (-0.264 to 0.068)

0.246

0.125 (-0.021 to 0.271)

0.094

 Model 2 d

  Estimate (SE) of Intercept

0.207 (0.540)

 

-0.490 (0.476)

 

  Vegetable-Fruit-Dairy diet

-0.092 (-0.272 to 0.088)

0.315

-0.023 (-0.181 to 0.136)

0.779

  Traditional Japanese diet

-0.088 (-0.254 to 0.079)

0.302

0.103 (-0.044 to 0.249)

0.170

Women (n =821)

 Model 1 c

  Estimate (SE) of Intercept

-0.458 (0.551)

 

-0.416 (0.460)

 

  Grain-Vegetable-Fruit diet

-0.026 (-0.199 to 0.148)

0.773

-0.093 (-0.238 to 0.052)

0.210

  Traditional Japanese diet

-0.149 (-0.291 to -0.007)

0.040

0.070 (-0.048 to 0.188)

0.247

 Model 2 d

  Estimate (SE) of Intercept

-0.534 (0.601)

 

-0.224 (0.500)

 

  Grain-Vegetable-Fruit diet

-0.024 (-0.198 to 0.150)

0.790

-0.090 (-0.235 to 0.055)

0.223

  Tradistional Japanese diet

-0.145 (-0.287 to -0.002)

0.047

0.070 (-0.048 to 0.189)

0.246

  1. a \(\text{Annual changes in region of interest (ROI)}\, (\%)=\frac{\text{relative volume of ROI}_\text{at baseline}-\text{relative volume of ROI}_\text{at follow-up}}{\text{relative volume of ROI}_\text{at baseline}}\div\frac{\text{follow-up time (days)}}{365.25}\times100\%\)
  2. bAnalyzed by the general linear model. participants in the Western diet were used as the reference group
  3. cAdjusted for baseline information on age (years; continuous), APOE genotype (APOE-ε4 carriers: 2/4, 3/4, 4/4, or APOE-ε4 noncarriers: 2/2, 2/3, 3/3), education level (≤ 9, 10 − 12, or ≥ 13 years), smoking status (never, former, or current), total physical activity (METs-h/day; continuous), and energy intake (kcal/day; continuous)
  4. dAdjusted for Model 1 plus baseline information on BMI (kg/m2; continuous), depressive symptoms (CES-D score; ≤15 or ≥ 16), and medical history (i.e., stroke, hypertension, heart disease, dyslipidemia, and diabetes; dichotomous yes or no responses, for each)