Table 3 Risk of metabolic syndrome among subjects based on stratification by genotypes of the rs301 variant

Coffee drinking (ref: No)

Yes

0.852

0.718–1.011

0.067

0.599

0.463–0.774

< 0.001

0.477

0.229–0.992

0.047

Sex (ref: Female)

Male

0.941

0.782–1.132

0.517

0.738

0.564–0.965

0.027

0.447

0.187–1.069

0.070

Age (ref: 30 to 40)

41 to 50

1.814

1.431–2.299

< 0.001

2.051

1.441–2.920

< 0.001

0.661

0.240–1.821

0.423

51 to 60

3.133

2.471–3.972

< 0.001

3.507

2.477–4.966

< 0.001

1.731

0.701–4.277

0.234

61 to 70

4.650

3.558–6.077

< 0.001

4.711

3.186–6.967

< 0.001

2.551

0.887–7.332

0.082

BMI (kg/m²) (ref: Normal)

Overweight

3.647

2.954–4.503

< 0.001

4.560

3.335–6.233

< 0.001

5.279

2.077–13.415

0.001

Obese

14.989

12.097–18.571

< 0.001

14.116

10.231–19.478

< 0.001

22.899

8.576–61.141

< 0.001

Smoking (ref: Never)

Former

0.766

0.591–0.992

0.043

1.325

0.925–1.898

0.125

1.192

0.334–4.261

0.787

Current

1.333

1.031–1.725

0.029

2.040

1.424–2.923

< 0.001

4.609

1.538–13.813

0.006

Alcohol intake (ref: Never)

Former

1.962

1.319–2.919

0.001

0.906

0.482–1.696

0.757

0.137

0.020–0.937

0.043

Current

1.193

0.886–1.607

0.246

1.492

1.001–2.222

0.049

0.659

0.206–2.109

0.482

Exercise (ref: No)

Aerobic

0.858

0.719–1.025

0.091

0.790

0.609–1.024

0.075

1.099

0.506–2.386

0.811

Non-Aerobic

0.777

0.511–1.181

0.237

0.761

0.419–1.383

0.370

0.582

0.103–3.281

0.540

Midnight snacking (ref: No)

Yes

1.192

1.004–1.415

0.045

1.087

0.846–1.395

0.514

1.571

0.716–3.448

0.260

Vegetarian diet (ref: No)

Former

1.398

0.947–2.066

0.092

0.943

0.542–1.644

0.837

0.274

0.035–2.125

0.216

Current

1.042

0.716–1.516

0.830

0.972

0.572–1.652

0.917

0.280

0.041–1.896

0.192