Table 4 Quality of Life Indicators before and after the intervention in the curcumin-piperine and placebo groups

Physical

Functioning

65.37 ± 12.85

66.29 ± 12.52

0.92 ± 2.41

0.057

67.24 ± 9.31

68.96 ± 8.59

1.72 ± 2.41

0.001

0.145

0.176

Role functioning/ physical

81.48 ± 17.80

88.88 ± 14.43

7.40 ± 11.63

0.003

82.75 ± 16.50

88.27 ± 15.07

5.51 ± 10.29

0.007

0.565

0.596

Role functioning/ emotional

92.59 ± 14.12

95.06 ± 12.06

2.46 ± 8.89

0.161

94.25 ± 15.60

94.25 ± 15.60

0

0.99

0.160

0.216

Energy/ fatigut

61.11 ± 7.25

63.14 ± 6.81

2.03 ± 2.50

< 0.001

61.40 ± 8.13

63.01 ± 6.92

1.60 ± 2.33

0.001

0.503

0.438

Emotional well being

63.77 ± 7.28

64.96 ± 6.95

1.18 ± 1.86

0.003

62.40 ± 7.36

63.50 ± 7.67

1.10 ± 1.81

0.003

0.806

0.462

Social functioning

85.18 ± 16.99

89.81 ± 14.72

4.62 ± 7.86

0.005

87.50 ± 11.57

90.94 ± 8.77

3.44 ± 7.39

0.018

0.771

0.612

Pain

89.45 ± 15.49

92.87 ± 14.17

3.41 ± 5.85

0.005

90.77 ± 11.49

97.75 ± 5.60

6.98 ± 7.51

0 < 001

0.007

0.006

General health

62.03 ± 9.32

62.22 ± 9.64

0.18 ± 1.68

0.574

59.82 ± 7.96

60.34 ± 8.01

0.51 ± 1.54

0.083

0.741

0.441