Interaction between CETP Taq1B polymorphism and dietary patterns on lipid profile and severity of coronary arteries stenosis in patients under coronary angiography: a cross-sectional study

AhmadiVasmehjani, Azam; SeyedHosseini, SeyedMostafa; Khayyatzadeh, SayyedSaeid; Madadizadeh, Farzan; Mazaheri-Naeini, Mahta; Yavari, Mahdie; Darabi, Zahra; Beigrezaei, Sara; Taftian, Marzieh; Arabi, Vahid; Motallaei, Maryam; Salehi-Abargouei, Amin; Nadjarzadeh, Azadeh

doi:10.1186/s12937-023-00899-w

Table 4 Interaction between the CETP TaqIB polymorphism and adherence to WDP on CVD risk factors

From: Interaction between CETP Taq1B polymorphism and dietary patterns on lipid profile and severity of coronary arteries stenosis in patients under coronary angiography: a cross-sectional study

Variables	Model Crude			P^a	P**	Model adjusted			P^b	P**
	CETP Taq1B genotype					CETP Taq1B genotype
	B1B1 n = 47	B1B2 n = 328	B2B2 n = 78			B1B1 n = 47	B1B2 n = 328	B2B2 n = 78
	mean ± SE	mean ± SE	mean ± SE			mean ± SE	mean ± SE	mean ± SE
HDL-c (mg/d)
Low	50.41 ± 3.09	49.29 ± 0.88	50.22 ± 2.26	0.86	0.42	49.83 ± 2.75	49.08 ± 0.91	51.22 ± 1.94	0.60	0.65
High	44.50 ± 1.53	47.53 ± 0.92	49.92 ± 1.60	0.13	0.42	45.52 ± 2.16	47.59 ± 0.87	49.16 ± 1.78	0.43	0.65
LDL-c (mg/dl)
Low	102.25 ± 8.64	96.48 ± 2.82	93.35 ± 6.23	0.69	0.09	103.62 ± 8.57	95.89 ± 2.85	93.96 ± 6.06	0.64	0.11
High	81.29 ± 5.71	100.66 ± 3.23	103.04 ± 8.89	0.07	0.09	83.02 ± 8.48	101.37 ± 3.44	99.37 ± 6.99	0.13	0.11
TC(mg/dl)
Low	188.65 ± 22.92	195.08 ± 8.40	202.91 ± 19.99	0.88	0.65	193.25 ± 25.34	193.95 ± 8.43	206.58 ± 17.91	0.81	0.26
High	209.14 ± 28.92	205.25 ± 7.61	191.29 ± 13.53	0.70	0.65	213.11 ± 19.11	207.87 ± 7.76	180.11 ± 15.76	0.25	0.26
TG(mg/dl)
Low	163.39 ± 23.40	161.79 ± 5.93	168.97 ± 18.98	0.90	0.46	170.77 ± 19.01	159.18 ± 6.32	175.24 ± 13.44	0.51	0.45
High	173.57 ± 18.95	140.99 ± 5.24	159.73 ± 15.86	0.07	0.46	176.76 ± 14.52	140.67 ± 5.89	161.50 ± 11.97	0.03	0.45
TG/HDL
Low	3.30 ± 0.43	3.38 ± 0.13	3.36 ± 0.31	0.97	0.22	3.45 ± 0.38	3.34 ± 0.12	3.45 ± 0.27	0.91	0.20
High	3.98 ± 0.47	3.09 ± 0.12	3.20 ± 0.27	0.05	0.22	4.01 ± 0.33	3.07 ± 0.13	3.28 ± 0.27	0.03	0.20
Gensisni score
Low	35.43 ± 9.90	36.95 ± 3.16	25.84 ± 5.27	0.30	0.26	38.49 ± 8.75	36.20 ± 2.91	28.51 ± 6.18	0.49	0.39
High	27.03 ± 7.90	34.03 ± 3.07	38.26 ± 8.14	0.54	0.26	25.01 ± 7.78	35.01 ± 3.16	36.39 ± 6.41	0.45	0.39
Syntax score
Low	9.95 ± 2.83	11.17 ± 0.96	8.27 ± 1.80	0.41	0.29	10.67 ± 2.72	11.01 ± 0.90	8.90 ± 1.92	0.61	0.45
High	8.66 ± 2.80	10.40 ± 0.92	12.35 ± 2.48	0.49	0.29	8.27 ± 2.41	10.68 ± 0.98	11.72 ± 1.98	0.53	0.45

WDP, western dietary pattern; BMI, body mass index; TC; total cholesterol, HDL-C; high-density lipoprotein cholesterol, LDL-C; low-density lipoprotein cholesterol, TG; triglyceride. Adherence to dietary patterns is considered two categories, “high” adherence and “low” adherence, according the median intake
Values are presented means ± standard errors (SEs), ^a P based on One- way ANOVA, ^b P adjusted for gender, smoking status, menopausal status, BMI, energy, medications, education, age. P** obtained from Two- way ANOVA both model crude and adjusted
P-Values < 0.05 were considered significant

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