Interaction between CETP Taq1B polymorphism and dietary patterns on lipid profile and severity of coronary arteries stenosis in patients under coronary angiography: a cross-sectional study

AhmadiVasmehjani, Azam; SeyedHosseini, SeyedMostafa; Khayyatzadeh, SayyedSaeid; Madadizadeh, Farzan; Mazaheri-Naeini, Mahta; Yavari, Mahdie; Darabi, Zahra; Beigrezaei, Sara; Taftian, Marzieh; Arabi, Vahid; Motallaei, Maryam; Salehi-Abargouei, Amin; Nadjarzadeh, Azadeh

doi:10.1186/s12937-023-00899-w

Table 3 Interaction between the CETP TaqIB polymorphism and adherence to TDP on CVD risk factors

From: Interaction between CETP Taq1B polymorphism and dietary patterns on lipid profile and severity of coronary arteries stenosis in patients under coronary angiography: a cross-sectional study

Variables	Model Crude			P^a	P**	Model adjusted			P^b	P**
	CETP Taq1B genotype					CETP Taq1B genotype
	B1B1 n = 47	B1B2 n = 328	B2B2 n = 78			B1B1 n = 47	B1B2 n = 328	B2B2 n = 78
	mean ± SE	mean ± SE	mean ± SE			mean ± SE	mean ± SE	mean ± SE
HDL-c (mg/d)
Low	47.15 ± 2.42	49.71 ± 0.97	52.19 ± 1.88	0.30	0.72	47.59 ± 2.57	49.65 ± 0.92	52.21 ± 2.0	0.33	0.64
High	46.66 ± 2.13	47.11 ± 0.81	48.25 ± 1.92	0.79	0.72	46.92 ± 2.15	47.16 ± 0.85	47.88 ± 1.67	0.91	0.64
LDL-c (mg/dl)
Low	92.42 ± 9.18	102.20 ± 3.32	105.67 ± 7.17	0.51	0.79	95.72 ± 8.97	101.81 ± 3.22	105.46 ± 6.99	0.69	0.78
High	87.42 ± 7.37	94.63 ± 2.91	92.03 ± 5.68	0.64	0.79	87.16 ± 7.49	94.56 ± 2.95	92.45 ± 5.81	0.64	0.78
TC(mg/dl)
Low	185.20 ± 26.23	211.39 ± 8.24	215.09 ± 21.96	0.56	0.23	196.22 ± 23.61	210.66 ± 8.48	211.75 ± 18.40	0.84	0.39
High	214.63 ± 28.54	189.06 ± 7.71	181.41 ± 11.32	0.38	0.23	215.06 ± 19.55	187.47 ± 7.71	183.39 ± 15.16	0.38	0.39
TG(mg/dl)
Low	136.56 ± 12.74	151.52 ± 5.52	153.02 ± 15.05	0.65	0.04	139.40 ± 14.86	151.78 ± 5.34	150.09 ± 11.58	0.73	0.02
High	198.40 ± 23.80	151.90 ± 5.84	173.84 ± 18.77	0.03	0.04	198.18 ± 17.34	150.79 ± 6.84	178.21 ± 13.44	0.01	0.02
TG/HDL
Low	3.02 ± 0.32	3.15 ± 0.12	2.90 ± 0.22	0.67	0.10	3.06 ± 0.32	3.16 ± 0.11	2.84 ± 0.25	0.51	0.04
High	4.30 ± 0.38	3.33 ± 0.13	3.60 ± 0.32	0.06	0.10	4.28 ± 0.36	3.30 ± 0.14	3.75 ± 0.28	0.03	0.04
Gensisni score
Low	25.81 ± 8.76	32.37 ± 2.91	25.56 ± 5.27	0.49	0.84	28.32 ± 7.54	32.11 ± 2.71	25.27 ± 5.88	0.54	0.76
High	34.49 ± 8.67	38.86 ± 3.32	37.91 ± 7.90	0.89	0.84	31.12 ± 8.63	39.32 ± 3.40	38.16 ± 6.69	0.67	0.76
Syntax score
Low	8.00 ± 3.10	10.10 ± 0.91	8.99 ± 2.13	0.70	0.93	8.91 ± 2.49	9.97 ± 0.89	9.03 ± 1.94	0.85	0.88
High	10.22 ± 2.63	11.53 ± 0.97	11.54 ± 2.24	0.89	0.93	9.54 ± 2.55	11.56 ± 1.00	11.83 ± 1.97	0.73	0.88

TDP, traditional dietary pattern; BMI, body mass index; TC; total cholesterol, HDL-C; high-density lipoprotein cholesterol, LDL-C; low-density lipoprotein cholesterol, TG; triglyceride. Adherence to dietary patterns is considered two categories, “high” adherence and “low” adherence, according the median intake
Values are presented means ± standard errors (SEs), ^a P based on One- way ANOVA, ^b P adjusted for gender, smoking status, menopausal status, BMI, energy, medications. P** obtained from Two- way ANOVA both model crude and adjusted
P-Values < 0.05 were considered significant

Back to article page

ISSN: 1475-2891

Contact us

General enquiries: journalsubmissions@springernature.com

Nutrition Journal

Contact us