Variables | Q1 (n = 6683) | Q2 (n = 6682) | Q3 (n = 6683) | Q4 (n = 6682) | P value |
---|---|---|---|---|---|
Male (%) | 53.9 | 60.3 | 65.0 | 68.6 | < 0.001 |
Age (years) | 57.4 ± 7.3 | 57.3 ± 7.5 | 57.2 ± 7.6 | 56.1 ± 8.0 | 0.001 |
White ethnicity (%) | 96.4 | 96.2 | 96.3 | 95.1 | < 0.001 |
Townsend deprivation index | −1.4 ± 2.9 | −1.7 ± 2.8 | −1.6 ± 2.9 | −1.3 ± 3.0 | < 0.001 |
College or university degree (%) | 39.2 | 40.4 | 39.4 | 35.9 | < 0.001 |
Household income (£) |  |  |  |  | < 0.001 |
 < 18,000 | 16.8 | 14.8 | 16.8 | 17.7 |  |
 18,000 to 30,999 | 23.1 | 23.4 | 23.2 | 24.1 |  |
 31,000 to 51,999 | 25.9 | 27.0 | 26.2 | 25.8 |  |
 52,000 to 100,000 | 19.8 | 20.7 | 20.4 | 19.2 |  |
 > 100,000 | 5.0 | 4.6 | 4.6 | 4.1 |  |
Sedentary behavior (%) | 44.1 | 41.5 | 44.2 | 47.2 | < 0.001 |
Smoking status (%) |  |  |  |  | < 0.001 |
 Never | 52.0 | 55.2 | 55.7 | 55.8 |  |
 Previous | 41.4 | 39.5 | 37.9 | 35.2 |  |
 Current | 6.6 | 5.3 | 6.4 | 9.0 |  |
Alcohol consumption (%) |  |  |  |  | < 0.001 |
 Never or special occasions only | 23.6 | 20.8 | 20.1 | 26.0 |  |
 1 to 3 times/month | 16.7 | 14.7 | 15.3 | 16.7 |  |
 1 to 4 times/week | 52.4 | 55.0 | 54.8 | 49.1 |  |
 Daily or almost daily | 7.3 | 9.5 | 9.7 | 8.2 |  |
Body mass index (kg/m2) | 32.2 ± 4.8 | 31.4 ± 4.5 | 31.2 ± 4.4 | 30.9 ± 4.4 | < 0.001 |
Waist circumference (cm) | 103.2 ± 10.4 | 102.2 ± 9.8 | 102.0 ± 9.6 | 102.0 ± 9.7 | < 0.001 |
Hypertension (%) | 70.7 | 68.1 | 67.8 | 66.7 | < 0.001 |
Diabetes (%) | 17.6 | 9.9 | 7.3 | 5.7 | < 0.001 |
Alanine aminotransferase (U/L) | 29.2 ± 16.8 | 29.1 ± 14.5 | 29.4 ± 15.7 | 30.0 ± 16.3 | 0.007 |
Gamma glutamyltransferase (U/L) | 47.3 ± 44.7 | 46.6 ± 42.0 | 47.7 ± 44.4 | 49.0 ± 44.3 | 0.014 |
Triglycerides (mmol/L) | 2.3 ± 1.1 | 2.4 ± 1.1 | 2.4 ± 1.2 | 2.5 ± 1.2 | < 0.001 |
Total cholesterol (mmol/L) | 5.6 ± 1.2 | 5.7 ± 1.2 | 5.7 ± 1.2 | 5.7 ± 1.2 | 0.004 |
Total energy intake (KJ) | 8110.8 ± 2095.0 | 8719.5 ± 2191.7 | 9004.5 ± 2243.3 | 9086.1 ± 2377.6 | < 0.001 |