Mushroom consumption and hyperuricemia: results from the National Institute for Longevity Sciences-Longitudinal Study of Aging and the National Health and Nutrition Examination Survey (2007-2018)

Table 4 ORs and corresponding 95% CIs for incident hyperuricemia by mushroom consumption (NILS-LSA; n = 1,738)^a

	Groups of mushroom consumption								P-trend
	Non-consumer		Middle			Highest
	OR	95% CI	OR	95% CI		OR	95% CI
Men (n = 799)
Mushroom consumption (g/day); mean (SD)	0 (-)		6.8 (3.3)			26.9 (12.9)
No. of participants	142		326			331
Model 1^b	1.00	Ref.	0.81	0.48	1.38	0.67	0.39	1.13	0.120
Model 2^c	1.00	Ref.	0.79	0.47	1.32	0.67	0.40	1.13	0.135
Model 3^d	1.00	Ref.	0.74	0.43	1.27	0.65	0.38	1.12	0.129
Women (n = 939)
Mushroom consumption (g/day); mean (SD)	0 (-)		6.6 (3.2)			26.5 (13.1)
No. of participants	184		370			385
Model 1^b	1.00	Ref.	0.94	0.51	1.74	0.86	0.46	1.60	0.620
Model 2^c	1.00	Ref.	0.99	0.53	1.86	0.89	0.48	1.66	0.684
Model 3^d	1.00	Ref.	1.03	0.55	1.91	0.88	0.47	1.63	0.613

^aAnalysis by Generalized estimating equation
^bAdjusted for baseline information on age (years; continuous), BMI (kg/m²; < 18.5, 18.5– < 25, ≥ 25), disease history (hypertension, dyslipidemia, diabetes; yes or no for each), eGFR (mL/min/1.73m²; continuous), serum UA concentration level (μmol/L), education (less than high school, high school, above high school), and follow-up time (days; continuous)
^cAdjusted for Model 1 + baseline information on smoking status (current smoker, others), alcohol drinking (current drinker, others), and total physical activity (METs-h/day; continuous)
^dAdjusted for Model 2 + baseline information on consumption (g/day; continuous) of fish and shellfish, meat, vegetables, and fruit, and energy intake (kcal/d; continuous)

ISSN: 1475-2891