Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial

Table 4 Effects of curcumin and/or coenzyme Q10 supplementation on lipid profile and body composition^a

Variables	CP group (n = 22)	QP group (n = 22)	CQ group (n = 22)	DP group (n = 22)	P_baseline	P_{between groups}
Lipid profile^b
TC, mg/dL					0.52	< 0.001
Week 0	217.4 ± 37.4	238.4 ± 37.9	228.2 ± 47.9	238.4 ± 68.1
Week 12	186.5 ± 30.4	228.3 ± 39.8	221.2 ± 40.7	237.7 ± 53.9
Mean difference	−30.9 ± 35.1	−10.1 ± 30.2	−7.0 ± 36.3	−0.7 ± 43.4
P_{within groups}	< 0.001	0.06	0.15	0.70
LDL-c, mg/dL					0.46	< 0.001
Week 0	89.4 ± 6.5	90.8 ± 8.6	96.3 ± 11.2	89.3 ± 10.1
Week 12	75.3 ± 5.4	88.5 ± 8.4	95.3 ± 11.4	87.3 ± 7.4
Mean difference	−14.1 ± 6.2	−2.3 ± 8.3	−1.0 ± 9.3	−2.0 ± 8.4
P_{within groups}	< 0.001	0.35	0.42	0.40
Body composition indices^c
Weight, Kg					0.07	0.19
Week 0	92.1 ± 8.2	94.0 ± 10.1	91.0 ± 10.8	92.1 ± 10.5
Week 12	90.1 ± 8.1	92.2 ± 15.8	89.1 ± 10.2	91.1 ± 10.1
Mean difference	−2.0 ± 7.6	−1.8 ± 12.6	−1.9 ± 9.7	−1.0 ± 9.5
P_{within groups}	0.07	0.09	0.08	0.15
BMI, Kg/m²					0.21	0.45
Week 0	30.0 ± 4.6	30.7 ± 4.9	29.7 ± 5.1	30.0 ± 4.7
Week 12	29.4 ± 4.2	30.1 ± 5.6	29.1 ± 5.0	29.7 ± 4.7
Mean difference	−0.6 ± 3.9	−0.6 ± 4.5	−0.6 ± 4.5	−0.3 ± 4.4
P_{within groups}	0.34	0.41	0.40	0.45

CP curcumin plus placebo, QP coenzyme Q10 plus placebo, CQ curcumin plus coenzyme Q10, DP double placebo, TC total cholesterol, LDL-c low density lipoprotein-cholesterol, BMI body mass index, TG triglyceride, HDL-c high density lipoprotein-cholesterol, WC waist circumference
^aData are expressed as mean ± standard deviation (SD). ^bValues of TG and HDL-c, which are parameters of lipid profile, are expressed in Table 2. ^cValues of WC, which is a variable of body composition, is expressed in Table 2

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