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Table 3 Associations between higher adherence to the MedDiet and outcomes

From: Female dietary patterns and outcomes of in vitro fertilization (IVF): a systematic literature review

Outcome

Author (year)

Sample size

Main finding

Measure of association

Biochemical pregnancy

Vujkovik (2010) [54]

161 couples

+

adjusted OR (95% CI) (ref not stated): 1.4 (1.0–1.9)

Karayiannis (2018) [49]

244 women

no appreciable association

adjusted RR (95% CI) Q1-Q3: 0.62 (0.28–1.36), 0.81 (0.39–1.65), 1.00 (ref)

Gaskins (2019) [48]

357 womena

no appreciable association

adjusted proportion (95% CI) Q1-Q4: 0.49 (0.41–0.57), 0.62 (0.53–0.69), 0.64 (0.55–0.72), 0.55 (0.47–0.63)

Sun (2019) [52]

167 women

no appreciable association

(binary) high adherence = 29.97%, low adherence = 31.75%

Clinical pregnancy

Karayiannis (2018) [49]

244 women

+ Age < 35 years

adjusted RR (as a continuous variable) (95% CI):

Age < 35 years 1.22 (1.05–1.43)

Age ≥ 35 1.00 (0.92–1.09)

adjusted RR Q1-Q3 (95%CI): all women 0.35 (0.16–0.78), 0.81 (0.41–1.59), 1.00 (ref)

Gaskins (2019) [48]

357 women1

no appreciable association

adjusted proportion (95% CI) Q1-Q4: 0.43 (0.35–0.50), 0.56 (0.47–0.64), 0.57 (0.48–0.66), 0.48 (0.40–0.56)

Ricci (2019) [50]

474 women

+ Age > 35b

adjusted RR of not achieving pregnancy Q1-Q3 (95% CI): Age ≤ 35 1 (ref), 0.96 (0.80–1.14), 0.99 (0.81–1.20)

Age > 35 1 (ref), 0.84 (0.70–1.00), 0.94 (0.81–1.20)

all women 1 (ref), 0.95 (0.86–1.05), 0.98 (0.87–1.09)

Sun (2019) [52]

167 women

no appreciable association

(binary) high adherence = 42.62%, low adherence = 50.94%

Live birth

Karayiannis (2018) [49]

244 women

+ Age < 35 years

adjusted RR (as a continuous variable) (95% CI):

Age < 35 1.25 (1.07–1.45)

Age ≥ 35 1.01 (0.93–1.11)

adjusted RR Q1-Q3 (95%CI): all women 0.32 (0.14–0.71), 0.78 (0.39–1.54), 1.00 (ref)

Gaskins (2019) [48]

357 women1

+ c

adjusted proportion (95% CI) Q1-Q4: 0.31 (0.25–0.39), 0.47 (0.39–0.55), 0.44 (0.36–0.49), 0.41 (0.34–0.49)

Ricci (2019) [50]

474 women

Null

adjusted RR Q1-Q3 (95% CI)

Age ≤ 35 1.00 (ref), 1.00 (0.81–1.21), 1.00 (0.79–1.26)

Age > 35 1.00 (ref), 0.96 (0.84–1.10), 0.97 (0.84–1.12)

all women 1 (ref), 1.00 (0.90–1.11), 0.99 (0.89–1.11)

  1. + = positive association
  2. a the sample contributed 608 ART ‘cycles’ and adjustments were made for unbalanced study design (different number of cycles contributed per woman)
  3. b positive association for Q2 vs Q1 only
  4. cQ2 vs Q1 only