Table 2 HR (95% CIs) of pancreatic cancer, by quartile of each fatty acid

Total fat

0.62

1.004(0.98-1.02)

 Range (gday-1)

7.46-60.03

60.03-73.57

73.57-88.02

88.02-304.73

 Median (gday-1)

50.46

67.25

80.19

99.88

 Cases/controls

20/11722

18/11732

14/11730

22/11720

 Multivariate HR (95% CI)

1

0.91(0.48-1.71)

0.54(0.24-1.21)

1.07(0.44-2.59)

 4:0

0.35

0.91 (0.76-1.10)

  Range (gday-1)

0.00-0.25

0.25-0.39

0.39-0.63

0.63-9.99

  Median (gday^-1)

0.17

0.31

0.49

1.03

  Cases/controls

20/11720

13/11732

23/11724

18/11727

  Multivariate HR (95% CI)

1

0.70(0.34-1.44)

1.001(0.51-1.92)

0.73(0.36-1.46)

 6:0

0.04

0.82 (0.68-0.99) *

  Range (gday-1)

0.00-0.19

0.19-0.30

0.30-0.52

0.52-9.99

  Median (gday^-1)

0.14

0.24

0.38

3.74

  Cases/controls

23/11719

14/11727

25/11733

12/11732

  Multivariate HR (95% CI)

1

0.64(0.32-1.28)

0.81(0.43-1.53)

0.51(0.24-1.04)

 8:0

0.01

0.84(0.74-0.96) *

  Range (gday-1)

0.00-0.18

0.18-0.27

0.27-0.55

0.55-10.00

  Median (gday^-1)

0.13

0.22

0.35

5.72

  Cases/controls

23/11709

17/11736

23/11725

11/11734

  Multivariate HR (95% CI)

1

0.70(0.37-1.32)

0.65(0.34-1.24)

0.38(0.18-0.79)*

 10:0

0.55

0.93 (0.75-1.16)

  Range (gday-1)

0.00-0.36

0.36-0.59

0.59-0.90

0.90-9.99

  Median (gday^-1)

0.24

0.47

0.72

1.25

  Cases/controls

19/11722

14/11727

20/11731

21/11724

  Multivariate HR (95% CI)

1

0.82(0.40-1.68)

1.09(0.56-2.13)

0.82(0.40-1.65)

 12:0

0.37

0.89 (0.69-1.14)

  Range (gday-1)

0.00-0.29

0.29-0.46

0.46-0.69

0.69-9.99

  Median (gday^-1)

0.21

0.37

0.55

0.94

  Cases/controls

20/11722

10/11733

22/11724

22/11725

  Multivariate HR (95% CI)

1

0.55(0.25-1.19)

1.13(0.58-2.18)

0.81(0.40-1.64)

 14:0

0.78

1.04 (0.77-1.41)

  Range (gday-1)

0.10-0.85

0.85-1.32

1.32-1.93

1.93-9.91

  Median (gday^-1)

0.57

1.08

1.59

2.47

  Cases/controls

17/11726

13/11732

19/11726

25/11720

  Multivariate HR (95% CI)

1

0.88(0.41-1.85)

1.17(0.57-2.43)

1.06(0.47-2.37)

 16:0

0.30

0.91 (0.77-1.08)

  Range (gday-1)

1.09-8.20

8.20-10.26

10.26-12.67

12.67-54.39

  Median (gday^-1)

6.84

9.27

11.34

14.73

  Cases/controls

19/11725

13/11732

19/11726

23/11721

  Multivariate HR (95% CI)

1

0.53(0.24-1.18)

0.72(0.32-1.63)

0.68(0.21-2.12)

 18:0

0.01

1.03(1.01-1.07)

  Range (gday-1)

0.61-18.17

18.17-24.65

24.65-30.90

30.90-234.84

  Median (gday^-1)

12.58

21.68

27.68

35.78

  Cases/controls

16/11728

18/11726

14/11732

26/11718

  Multivariate HR (95% CI)

1

1.21(0.58-2.54)

1.24(0.54-2.87)

2.57(1.03-6.41)*

 20:0

0.33

-

  Range (gday-1)

0.00-0.09

0.09-0.14

0.14-0.18

0.18-1.08

  Median (gday^-1)

0.06

0.12

0.16

0.21

  Cases/controls

21/11722

10/11712

20/11738

23/11732

  Multivariate HR (95% CI)

1

0.53(0.24-1.18)

0.97(0.47-2.01)

1.25(0.53-2.92)

 22:0

0.01

-

  Range (gday-1)

0.00-0.08

0.08-0.11

0.11-0.15

0.15-1.08

  Median (gday^-1)

0.05

0.10

0.13

0.17

  Cases/controls

18/11719

13/11726

20/11738

23/11721

  Multivariate HR (95% CI)

1

0.74(0.34-1.59)

1.47(0.70-3.08)

1.80(0.76-4.28)

 24:0

<0.001

0.69(0.60-0.80) *

  Range (gday-1)

0.00-2.60

2.60-3.69

3.69-4.82

4.82-9.99

  Median (gday^-1)

1.90

3.17

4.20

5.80

  Cases/controls

36/11704

8/11737

13/11731

17/11726

  Multivariate HR (95% CI)

1

0.24(0.11-0.52) *

0.36(0.18-0.69)*

0.42(0.22-0.81)*

 Odd carbon Fatty acids (13:0,15:0,17:0)

<0.001

0.76(0.67-0.85) *

  Range (gday-1)

0.00-1.65

1.65-3.07

3.07-5.85

5.85-10.00

  Median (gday^-1)

1.24

2.22

4.29

7.78

  Cases/controls

32/11713

19/11725

15/11729

8/11737

  Multivariate HR (95% CI)

1

0.72(0.40-1.28)

0.49(0.26-0.91)*

0.27(0.12-0.61)*

 Long Chain fatty acids (>20C)

<0.001

0.71(0.61-0.82) *

  Range (gday-1)

0.00-2.79

2.79-3.95

3.95-5.15

5.15-10.80

  Median (gday^-1)

2.05

3.41

4.50

6.18

  Cases/controls

36/11709

8/11733

13/11730

17/11726

  Multivariate HR (95% CI)

1

0.24(0.11-0.52) *

0.36(0.18-0.69)*

0.42(0.22-0.81)*

Total SFA

0.01

1.05 (1.01-1.09) *

 Range (gday-1)

1.78-30.28

30.28-39.22

39.22-47.94

47.94-270.28

 Median (gday^-1)

23.72

35.12

43.29

54.77

 Cases/controls

19/11725

18/11725

11/11736

26/11718

 Multivariate HR (95% CI)

1

0.95(0.46-1.96)

0.73(0.29-1.82)

1.63(0.56-4.75)

 16:1 undifferentiated

0.06

0.50(0.24-1.03)

  Range (gday-1)

0.026-0.54

0.54-0.76

0.76-1.03

1.03-7.53

  Median (gday^-1)

0.41

0.65

0.88

1.28

  Cases/controls

23/11718

14/11731

15/11730

22/11725

  Multivariate HR (95% CI)

1

0.54(0.27-1.08)

0.50(0.25-1.03)

0.42(0.20-0.90)*

 18:1 undifferentiated

0.04

0.92(0.85-0.99) *

  Range (gday-1)

1.38-13.57

13.57-17.16

17.16-21.33

21.33-80.80

  Median (gday^-1)

11.22

15.39

19.04

24.89

  Cases/controls

19/11725

20/11724

19/11727

16/11728

  Multivariate HR (95% CI)

1

0.65(0.32-1.32)

0.54(0.23-1.25)

0.34(0.11-1.05)

 20:1

0.91

1.00(0.91-1.10)

  Range (gday-1)

0.00-0.16

0.16-.020

0.20-0.29

0.29-9.99

  Median (gday^-1)

0.12

0.17

0.23

4.14

  Cases/controls

16/11566

17/11575

21/11573

20/11580

  Multivariate HR (95% CI)

1

0.84(0.41-1.71)

1.39(0.69-2.79)

1.12(0.57-2.20)

Total MUFA

0.036

0.92(0.86-0.99) *

 Range (gday-1)

1.58-14.59

14.59-18.46

18.46-22.94

22.94-89.58

 Median (gday^-1)

12.09

16.55

20.47

26.74

 Cases/controls

19/11725

20/11724

19/11726

16/11729

 Multivariate HR (95% CI)

1

0.68(0.34-1.36)

0.50(0.22-1.16)

0.32(0.10.0.99)*

 20:2n-6

0.81

-

  Range (gday-1)

0.00-0.003

0.003-0.006

0.006-0.009

0.009-0.096

  Median (gday^-1)

0.00

0.00

0.01

0.01

  Cases/controls

17/11214

19/12240

20/11671

18/11779

  Multivariate HR (95% CI)

1

1.67(0.84-3.32)

1.90(0.95-3.80)

1.60(0.76-3.39)

 18:2n-6

0.78

0.97(0.83-1.14)

  Range (gday-1)

0.00-0.79

0.79-1.67

1.67-2.66

2.66-37.93

  Median (gday^-1)

0.18

1.23

2.12

3.61

  Cases/controls

22/11685

18/11762

19/11729

15/11728

  Multivariate HR (95% CI)

1

1.24(0.65-2.37)

1.26(0.66-2.41)

0.95(0.46-1.96)

 18:2 n-6 (CLA)

0.39

-

  Range (gday-1)

0.00-0.00

0.00-0.00

0.00-0.00

0.00-0.20

  Median (gday^-1)

0.00

0.00

0.00

0.01

  Cases/controls

40/22510

1/928

14/10440

19/13026

  Multivariate HR (95% CI)

1

0.66(0.09-4.83)

0.94(0.50-1.75)

0.95(0.52-1.70)

 18:2 Undifferentiated

0.08

0.92(0.84-1.01)

  Range (gday-1)

0.47-5.71

5.71-7.41

7.41-9.76

9.76-123.04

  Median (gday^-1)

4.68

6.56

8.39

12.56

  Cases/controls

23/11721

22/11723

13/11732

16/11728

  Multivariate HR (95% CI)

1

0.61(0.32-1.17)

0.40(0.18-0.88)*

0.47(0.19-1.15)

 18:3 Undifferentiated

0.14

0.31(0.06-1.48)

  Range (gday-1)

0.09-0.56

0.56-0.72

0.72-0.91

0.91-6.08

  Median (gday^-1)

0.46

0.64

0.80

1.06

  Cases/controls

20/11715

18/11734

16/11722

20/11733

  Multivariate HR (95% CI)

1

0.82(0.40-1.69)

0.63(0.27-1.47)

0.68(0.24-1.89)

 20:4 Undifferentiated

0.73

0.98(0.88-1.08)

  Range (gday-1)

0.00-0.17

0.17-0.25

0.25-0.44

0.44-9.99

  Median (gday^-1)

0.13

0.21

0.31

4.77

  Cases/controls

23/11464

20/11486

17/11482

13/11486

  Multivariate HR (95% CI)

1

0.87(0.47-1.59)

0.66(0.34-1.27)

0.38(0.18-0.78)*

 20:5n-3(EPA)

0.74

-

  Range (gday-1)

0.00-0.01

0.01-0.02

0.02-0.04

0.04-1.59

  Median (gday^-1)

0.00

0.01

0.02

0.06

  Cases/controls

19/11686

21/11696

17/11791

17/11731

  Multivariate HR (95% CI)

1

1.19(0.63-2.23)

0.95(0.48-1.90)

0.84(0.40-1.75)

 22:5n-3(DPA)

0.12

-

  Range (gday-1)

0.00-0.01

0.01-0.03

0.03-0.05

0.05-0.55

  Median (gday^-1)

0.01

0.02

0.04

0.06

  Cases/controls

20/11689

19/11744

17/11699

18/11772

  Multivariate HR (95% CI)

1

1.00(0.53-1.88)

0.95(0.49-1.84)

0.66(0.33-1.35)

 18:3n-3(ALA)

0.45

1.88(0.35-9.90)

  Range (gday-1)

0.00-0.02

0.02-0.03

0.03-0.05

0.05-4.71

  Median (gday^-1)

0.02

0.03

0.04

0.08

  Cases/controls

19/11712

14/11692

19/11764

22/11736

  Multivariate HR (95% CI)

1

0.76(0.36-1.59)

1.18(0.57-2.41)

1.64(0.77-3.48)

 22:6n-3(DHA)

0.28

0.09(0.001-7.25)

  Range (gday-1)

0.00-0.03

0.03-0.06

0.06-0.09

0.09-1.62

  Median (gday^-1)

0.02

0.04

0.07

0.13

  Cases/controls

20/11688

20/11738

15/11750

19/11728

  Multivariate HR (95% CI)

1

1.05(0.56-1.97)

0.81(0.41-1.63)

0.69(0.34-1.39)

Total PUFA^a

0.05

0.91(0.84-1.00)

 Range (gday-1)

0.66-6.67

6.67-8.62

8.62-11.29

11.29-125.45

 Median (gday^-1)

5.49

7.64

9.74

14.38

 Cases/controls

23/11721

22/11722

11/11734

18/11727

 Multivariate HR (95% CI)

1

0.72(0.38-1.35)

0.24(0.10-0.57) *

0.48(0.19-1.17)

Total n-3^a

0.52

0.52(0.07-3.76)

 Range (gday-1)

0.00-0.10

0.10-0.16

0.16-0.24

0.24-4.90

 Median (gday^-1)

0.07

0.13

0.19

0.33

 Cases/controls

17/11716

23/11717

17/11738

17/11733

 Multivariate HR (95% CI)

1

1.42(0.75-2.69)

1.11(0.54-2.25)

0.70(0.32-1.53)

Total n-6^a

0.77

0.97(0.83-1.14)

 Range (gday-1)

0.00-0.79

0.79-1.68

1.68-2.68

2.68-37.93

 Median (gday^-1)

0.19

1.24

2.12

3.61

 Cases/controls

22/11721

18/11727

19/11722

15/11734

 Multivariate HR (95% CI)

1

1.24(0.65-2.39)

1.26(0.66-2.42)

0.95(0.46-1.96)

Total trans

0.05

1.09(0.99-1.20)

 Range (gday-1)

0.00-4.60

4.60-6.56

6.56-8.35

8.35-70.12

 Median (gday^-1)

3.01

5.67

7.48

9.66

 Cases/controls

20/11725

16/11727

15/11731

25/11721

 Multivariate HR (95% CI)

1

0.89(0.43-1.83)

1.10(0.51-2.39)

1.92(0.84-4.41)