Regular consumption of soft drinks is associated with type 2 diabetes incidence in Mexican adults: findings from a prospective cohort study

Table 2 Risk of Type 2 Diabetes according to categories of soft drinks intake in participants from HWCS (n = 1445)

	Consumption level at baseline
	< 1/week	1–4 /week	> 5/week	p _trend^a
Median (IQR), servings per week	0.2 (0.1–0.2)	1.5 (1.1–3.1)	7.1 (6.0–10.0)	< 0.001
n	361	770	314
Cases of type 2 diabetes (n = 109)	18	56	35
Person-years	2371.8	5113.4	2040.9
Crude incidence rate (per 1000)	7.6 (4.8–12.0)	11.0 (8.4–14.2)	17.1 (12.3–23.8)
Model 1 - Age-adjusted, HR (95% CI)	Ref.	1.5 (0.9–2.5)	2.3 (1.3–4.0)	0.004
Model 2 - Multivariate-adjusted^b	Ref.	1.3 (0.7–2.2)	1.9 (1.0–3.5)	0.040
Model 3 - Model 2 + hypertension, HR (95% CI)	Ref.	1.3 (0.7–2.2)	1.8 (1.0–3.3)	0.046
Model 4 - Model 2 + baseline BMI, HR (95% CI)	Ref.	1.0 (0.6–1.7)	1.5 (0.8–2.8)	0.094
Model 5 - Model 2 + abdominal obesity, HR (95% CI)	Ref.	1.1 (0.6–1.9)	1.6 (0.8–3.0)	0.083

Abbreviations: HWCS Health Workers Cohort Study, IQR Interquartile range, HR Hazard risk, CI Confidence interval, BMI Body mass index
^aA linear trend in the HR for each of the soft drinks categories was evaluated by including a continuous variable in the model representing the median values of each of soft drinks intake
^bAdjusted for baseline covariates: age centered, sex, total energy intake, physical activity, smoking status, family history of diabetes, and alcohol intake at baseline (tertiles), level of education

ISSN: 1475-2891