| |
CAD cases
|
CAD controls
|
P
|
|---|
|
N = 711
|
N = 638
| |
|---|
|
Age (years)
|
66.64 ± 7.84
|
66.37 ± 7.82
|
0.531
|
|
Telomere length (T/S ratio)
|
1.00 ± 0.23
|
1.02 ± 0.24
|
0.100
|
|
Plasma fatty acid (% of total)
|
|
n-3 fatty acid (%)
|
2.63 (2.04, 3.69)
|
2.83 (2.11, 4.02)
|
0.013
|
|
18:3 (n-3) ALA (%)
|
0.28 (0.21, 0.38)
|
0.28 (0.22, 0.38)
|
0.310
|
|
20:5 (n-3) EPA (%)
|
0.39 (0.31, 0.49)
|
0.42 (0.32, 0.53)
|
0.002
|
|
22:6 (n-3) DHA (%)
|
1.92 (1.38, 2.79)
|
2.02 (1.45, 3.05)
|
0.020
|
|
n-6 fatty acid (%)
|
45.07 ± 4.68
|
45.43 ± 4.81
|
0.165
|
|
18:2(n-6) LA (%)
|
36.14 ± 4.63
|
36.43 ± 4.68
|
0.252
|
|
18:3(n-6) GLA (%)
|
0.19 (0.13, 0.29)
|
0.19 (0.13, 0.29)
|
0.824
|
|
20:3(n-6) DGLA (%)
|
0.88 (0.67, 1.13)
|
0.87 (0.69, 1.10)
|
0.652
|
|
20:4(n-6) AA (%)
|
7.57 ± 1.68
|
7.67 ± 1.79
|
0.328
|
|
n6:n3 ratio
|
17.02 (11.98, 22.10)
|
16.14 (10.93, 21.62)
|
0.053
|
|
Gender (%male)
|
459 (64.56%)
|
401 (62.85%)
|
0.516
|
|
rs529143
| | |
0.759
|
|
AA
|
522 (75.98%)
|
461 (74.47%)
| |
|
AC
|
155 (22.56%)
|
150 (24.23%)
| |
|
CC
|
10 (1.46%)
|
8 (1.29%)
| |
|
MAF
|
0.127
|
0.134
| |
- Data was presented as Mean ± Standard Deviation (SD) for normally distributed variables, median (interquartile range) for non-normally distributed variables or N (%) for categorical variables
- ALA α-Linolenic acid; EPA Eicosapentaenoic acid; DHA Docosahexaenoic acid; LA Linoleic acid; GLA γ-Linolenic acid; DGLA Dihomo-γ-linolenic acid; AA Arachidonic acid; MAF Minor allele frequency
