Fig. 4From: Gut microbiota-associated metabolite trimethylamine N-Oxide and the risk of stroke: a systematic review and dose–response meta-analysisDose–response association between the circulating trimethylamine N-oxide (TMAO) concentration and stroke risk. Linear relation (solid line) and 95% confidence interval (CI) (dashed lines) of pooled odds ratio (OR) of stroke prevalence by 1 μmol/L increment of circulating TMAO. As shown in Fig. 4, there is a sharp increase in the related curve of stroke risk between the dosages of ̴ 0–10 μmol/L of circulating TMAO and after that dose, a slight reduction in risk of stroke is observedBack to article page