Low folate intake and serum levels are associated with higher body mass index and abdominal fat accumulation: a case control study

Table 4 Associations between anthropometric parameters and folate intake, folate serum concentrations, and genes involved in folate metabolism in people aged 20–40 years; n = 421

	FM [%]			Waist circumference [m]			Hip circumference [m]			WHR
	ß	partial η2	p	ß	partial η2	p	ß	partial η2	p	ß	partial η2	p
Sex, male	−0.50	0.205	< 0.001	0.24	0.035	< 0.001	−0.26	0.047	< 0.001	0.21	0.030	< 0.001
Low DFE intake [μg/day]	0.11	0.014	< 0.05	0.11	0.012	< 0.05	0.38	0.002	NS	0.06	0.002	NS
Serum folate level [ng/ml]	−0.09	0.012	< 0.05	− 0.17	0.042	< 0.001	− 0.06	0.003	NS	−0.13	0.061	< 0.05
DHFR, major allele	0.02	0.001	NS	0.01	0.012	NS	0.15	0.005	NS	−0.03	0.001	NS
MTHFR, major allele	−0.02	0.001	NS	−0.00	0	NS	0.65	0.000	NS	0.04	0.001	NS

p values < 0.05 were considered significant
Abbreviations: FM Fat mass, NS Not significant, WHR Waist-hip ratio
The regression models were adjusted for total energy intake and diet quality (as continuous), and misreporting and physical activity (as categorical)

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