Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial

Table 2 Differences between experimental groups (48 mg and 96 mg sucralose) and control group at Wk0 and Wk10 OGTT

	(I) Group	(J) Group	Media difference (I-J)	Standard error	p	95% Confidence interval
	(I) Group	(J) Group	Media difference (I-J)	Standard error	p	Lower Bound	Upper Bound
Glucose, AUC	Control	48 mg	-1537.81	603.48	0.03^a	-2995.85	−79.77
	Control	96 mg	− 509.85	598.28	1.00	− 1955.34	935.64
	48 mg	Control	1537.81	603.48	0.03^a	79.77	2995.85
	48 mg	96 mg	1027.96	617.01	0.29	−462.79	2518.70
	96 mg	Control	509.85	598.28	1.00	−935.64	1955.34
	96 mg	48 mg	− 1027.96	617.01	0.29	− 2518.70	462.79
Insulin, AUC	Control	48 mg	− 1104.65	954.05	0.75	− 3409.70	1200.40
	Control	96 mg	1547.55	945.84	0.31	− 737.66	3832.77
	48 mg	Control	1104.65	954.05	0.75	− 1200.40	3409.70
	48 mg	96 mg	2652.20^a	975.45	0.02	295.45	5008.96
	96 mg	Control	− 1547.55	945.84	0.31	− 3832.77	737.66
	96 mg	48 mg	−2652.20^a	975.45	0.02	−5008.96	−295.45

^a The mean difference is significant at 0.05 level. Two-way ANOVA adjustment for multiple comparisons with Bonferroni

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