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Table 5 Inflammatory parameters before and after 8 weeks of HPN

From: Efficacy of a long-term home parenteral nutrition regimen containing fish oil-derived n-3 polyunsaturated fatty acids: a single-centre, randomized, double blind study

Inflammatory parameter Test group (MCT/LCT/n-3 PUFA) N = 11 Control group (MCT/LCT) N = 11
IL-6 (ng/L)
 (reference range < 5 ng/L)
  Baseline 5.473 ± 2.501 7.050 ± 5.432
  V2 (8 weeks HPN) 9.145 ± 8.614 4.364 ± 2.448
Mean treatment difference (V2-BL) = 4.8 ng/L, CI 95 [− 0.5; 10.1], p = 0.0745, t-test
IL-10 (ng/L)
 (reference range < 5 ng/L)
  Baseline 5.000 ± 0.000 5.033 ± 0.115
  V2 (8 weeks HPN) 5.000 ± 0.000 5.027 ± 0.090
Mean treatment difference (V2-BL) = − 0.03 ng/L, CI 95 [− 0.09; 0.03], p = 0.3062, t-test
TNF-alpha (ng/L)
 (reference range < 15 ng/L)
  Baseline 11.918 ± 6.506 13.175 ± 6.996
  V2 (8 weeks HPN) 10.673 ± 4.382 10.645 ± 4.457
Mean treatment difference (V2-BL) = 0.9 ng/L, CI 95 [− 2.5; 4.3], p = 0.5801, t-test
CRP (mg/dL)*
 (reference range < 0.50 mg/dL)
  Baseline 0.691 ± 0.595 0.977 ± 1.370
  V2 (8 weeks HPN) 1.453 ± 1.903 0.745 ± 0.541
Mean treatment difference (V2-BL) = 0.6 mg/L, CI 95 [− 0.4; 1.6], p = 0.2231, t-test
  1. *Number of values (test group): N(Baseline) = 14; N(V2) = 15 Number of values (control group): N(Baseline) = 18; N(V2) = 18