Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment

Brunvoll, Sonja H.; Thune, Inger; Frydenberg, Hanne; Flote, Vidar G.; Bertheussen, Gro F.; Schlichting, Ellen; Bjerve, Kristian S.; Hjartåker, Anette

doi:10.1186/s12937-018-0402-6

Table 3 Daily intakes by median, median E % and quartiles (P_{25, 75}), n = 49

From: Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment

Dietary intake	PFD									FFQ
	Time 0			Time 6			Time 12			Time 0			Time 12
	E%	Median	P₂₅, ₇₅	E%	Median	P₂₅, ₇₅	E%	Median	P₂₅, ₇₅	E%	Median	P₂₅, ₇₅	E%	Median	P₂₅, ₇₅
Energy, kJ		7557	6468–8834		6937	6119–8586		7419	6502–8071		8345*	7123–10,393		8254^†	6746–9656
Carbohydrate, g	37	160	143–184	40	165	129–194	39	170	136–192	40*	197*	157–249	40^†	196^†	155–228
Sugar, g	7	28	19–41	5	25	14–45	6	25*	15–34	4*	20*	16–37	4^†	16^†§	9–31
Fibre, g		19	14–23		18	13–22		18	15–23		27*	20–31		27^†	20–33
Protein, g	17	74	64–85	17	72	62–88	17	73	64–84	18	84*	70–106	17	79^†	68–103
Alcohol, g	4	10	6–18	4	9	3–16	5	14	4–20	3	11	6–18	3^†	7^†§	3–15
Fat, g	39	77	68–94	36	70*	58–81	36	74	60–89	35*	82	64–100	35^†	76	58–99
SFA, g	15	30	24–36	14	27*	21–31	14	28	22–34	12*	28	23–35	12^†	27	19–33
PUFA, g	6	12	10–14	6	11	9–13	6	11	10–13	6	13*	11–18	6^†	13^†	11–17
Total n-6, g	4	9	7–11	4	8*	6–10	4	8	7–10	4	9*	7–13	4	9^†	7–12
Total n-3, mg	1.3	3007	2309–3801	1.3	2941	1750–3368	1.3	2643	1713–4104	1.6*	3499*	2732–4841	1.5^†	3544^†	2499–4669
EPA, mg		372	160–605		358	148–519		403	171–605		472*	314–743		470^†	318–645
DHA, mg		596	300–924		567	260–843		636	258–927		748*	500–1116		689^†	478–1006
Fish, fish products, g		73	34–106		79	39–116		67^‡	27–104		77	53–113		79	49–100
Fatty fish, g		21	4–42		16	4–37		26	4–46		21	13–40		20	13–30
Supplements, n (%)		30 (61)			26 (53)			29 (59)			34 (69)			30 (61)
With n-3, n (%)		24 (49)			18 (37)			22 (45)			29 (59)			23 (47)
Total n-3, mg ‖		628	356–1042		997	503–1215		595	300–1215		606	224–1368		619^†	417–1711
EPA, mg ‖		163	76–198		180	121–202		133	92–198		124	54–3411		157	124–279
DHA, mg ‖		224	104–273		247	166–277		183	124–273		170	75–470		216	170–384

E% Energy percent, PFD pre-coded food diary, FFQ food frequency questionnaire
time 0: around surgery (FFQ: presurgery, PFD: postsurgery), time 6: 6 months postsurgery, time 12: 12 months postsurgery
EPA (20:5n-3), DHA (22:6n-3)
‖ within group taking n-3 supplements
* Significantly different from PFD time 0. The significance level is 0.05
^‡ Significantly different from PFD time 6. The significance level is 0.05
^† Significantly different from PFD time 12. The significance level is 0.05
^§ Significantly different from FFQ time 0. The significance level is 0.05

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