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Table 1 Characteristics of studies included in the meta-analysis

From: Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials

Study Region Type Duration Inclusion criteria   Intervention N Age Male
Metabolic syndrome
 Rahmani et al. 2016 [23] Iran RCT double-blind 8 weeks Patients with symptoms of MetS (NCEP-ATP III) and diagnosis of NAFLD Case Amorphous dispersion Curcumin (amorphous dispersion preparation, equivalent to 70 mg/d curcuminoids) 37 46.37 ± 11.57 19
Control Placebo 40 48.95 ± 9.78 19
 Amin et al. 2015 [26] Pakistan RCT double-blind 8 weeks Patients with ≥ 3 features of MetS, prediabetes, dyslipidemia and prehypertension Case Turmeric powder 2.4 g/d 63 42.40 ± 13.70 NA
Control Placebo 63 41.57 ± 12.80 NA
 Yang et al. 2014 [27] Taiwan RCT double-blind 12 weeks Patients with diagnosis of MetS (NCEP-ATP III) Case Turmeric extract (equivalent to 1890 mg/d curcuminods) 30 59.03 ± 10.10 12
Control Placebo 29 59.61 ± 14.09 17
Type 2 diabetes mellitus
 Rahimi et al. 2016 [24] Iran RCT double-blind 3 months Type 2 Diabetic patients Case Curcumin (nano-micelle 80 mg/day) 35 56.34 ± 11.17 17
Control placebo 35 60.95 ± 10.77 14
 Selvi et al. 2015 [25] India RCT 4 weeks Type 2 diabetic patients Case Turmeric powder 2 g/day +Metformin 30 47.00 ± 7.17 30
Control Metformin (1 g/day) 30 46.80 ± 6.10 30
 Chuengsamarn et al. 2014 [28] Thailand RCT double-blind 6 months Type 2 diabetic patients Case Turmeric extract (equivalent to 1500 mg/d curcuminods) 107 59.16 ± 11.04 50
Control Placebo 106 59.58 ± 10.71 47
 Usharani et al. 2008 [15] India RCT 8 weeks Type 2 diabetic patients Case Turmeric extract (equivalent to 600 mg/day curcuminoids) 23 55.52 ± 10.76 12
Control Placebo 21 49.75 ± 8.18 11
  1. MetS metabolic syndrome, NAFLD nonalcoholic fatty liver disease, NCEP-ATP III National Cholesterol Education Program Adult Treatment Panel III, a diagnostic guideline of MetS, RCT randomized controlled trial, NA not available
  2. Values are expressed as mean ± SD