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Table 5 Adverse events reported during apple extract and placebo administration in the study. There were no statistical diffrences between the groups

From: The effect of an apple polyphenol extract rich in epicatechin and flavan-3-ol oligomers on brachial artery flow-mediated vasodilatory function in volunteers with elevated blood pressure

Description Epicatechin N (%) Placebo N (%)
Nasopharyngitis 5 (8.6) 3 (5.1)
Dyspepsia 2 (3.4) 2 (3.4)
Headache 15 (25.9) 14 (23.7)
Migraine 1 (1.7) 2 (3.4)
Dizziness 1 (1.7) 2 (3.4)
Ligament sprain 1 (1.7) 2 (3.4)
Gammaglutamyltransferase increased 1 (1.7) 2 (3.4)