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Table 6 Effects of lactose malabsorption on gastrointestinal symptoms

From: Effects of cow’s milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study

1 h

Absorbers (n=170)

Malabsorbers (n=430)

 

A1

A2

GEE estimate

A1

A2

GEE estimate

 

Median

Range

Median

Range

Estimate

SE

P

Median

Range

Median

Range

Estimate

SE

P

Borborygmus

3

0–6

2

0–6

1.562

0.218

<0.0001

3

0–6

2

0–5

1.244

0.116

<0.0001

Flatulence

3

0–6

2

0–5

1.826

0.212

<0.0001

2

0–6

1

0–5

1.395

0.119

<0.0001

Bloating

2

0–6

1

0–5

1.698

0.201

<0.0001

2

0–6

1

0–6

1.406

0.12

<0.0001

Abdominal Pain

1

0–5

0

0–4

1.552

0.206

<0.0001

0

0–5

0

0–5

0.396

0.107

0.0002

Stool Frequency

1

0–5

0

0–4

1.328

0.212

<0.0001

0

0–5

0

0–3

0.518

0.121

<0.0001

Stool Consistency

1

0–5

0

0–4

1.339

0.207

<0.0001

0

0–5

0

0–4

0.566

0.128

<0.0001

3 h

Absorbers (n=170)

Malabsorbers (n=430)

 

A1

A2

GEE estimate

A1

A2

GEE estimate

 

Median

Range

Median

Range

Estimate

SE

P

Median

Range

Median

Range

Estimate

SE

P

Borborygmus

3

0–5

2

0–5

1.701

0.206

<0.0001

3

0–6

2

0–6

2.022

0.124

<0.0001

Flatulence

3

0–5

2

0–5

1.424

0.199

<0.0001

3

0–6

2

0–5

2.079

0.133

<0.0001

Bloating

3

0–5

2

0–5

1.617

0.196

<0.0001

3

0–6

2

0–4

2.066

0.125

<0.0001

Abdominal Pain

2

0–6

0

0–4

1.375

0.204

<0.0001

2

0–6

0

0–4

2.149

0.134

<0.0001

Stool Frequency

1

0–5

0

0–3

1.866

0.222

<0.0001

2

0–5

0

0–3

2.454

0.136

<0.0001

Stool Consistency

1

0–5

0

0–4

1.904

0.216

<0.0001

2

0–5

0

0–3

2.586

0.146

<0.0001

12 ha

Absorbers (n=117)

Malabsorbers (n=283)

 

A1

A2

GEE estimate

A1

A2

GEE estimate

 

Median

Range

Median

Range

Estimate

SE

P

Median

Range

Median

Range

Estimate

SE

P

Borborygmus

0

0–2

0

0–2

–0.479

0.375

0.202

0

0–2

0

0–2

0.317

0.211

0.133

Flatulence

1

0–3

0

0–3

0.165

0.251

0.509

0

0–3

0

0–2

0.297

0.159

0.062

Bloating

2

0–4

1

0–4

1.074

0.242

<0.0001

2

0–5

1

0–4

0.812

0.15

<0.0001

Abdominal Pain

2

0–3

1

0–3

2.239

0.253

<0.0001

2

0–5

1

0–3

1.793

0.156

<0.0001

Stool Frequency

1

0–3

0

0–2

1.618

0.282

<0.0001

1

0–2

0

0–2

1.854

0.192

<0.0001

Stool Consistency

1

0–2

0

0–1

1.988

0.291

<0.0001

1

0–3

0

0–2

2.077

0.183

<0.0001

  1. A1 conventional milk containing A1 and A2 β-casein, A2 milk containing A2 β-casein
  2. aThe VAS was not assessed at 12 h in Shanghai
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Nutrition Journal

ISSN: 1475-2891

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