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Table 4 Proportions of subjects with improvements in gastrointestinal symptoms after consuming milk containing A2 β-casein relative to milk containing A1 β-casein (all study sites combined)

From: Effects of cow’s milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study

Measurement

Improvement

Borborygmus

Flatulence

Bloating

 

Abdominal Pain

  

n

%

n

%

n

%

n

%

1 h (n=600)

No symptom

50

8.3%

61

10.2%

112

18.7%

119

19.8%

Significant improvement

9

1.5%

9

1.5%

6

1.0%

1

0.2%

Slight improvement

310

51.7%

314

52.3%

279

46.5%

88

14.7%

No difference

231

38.5%

216

36.0%

203

33.8%

392

65.3%

3 h (n=600)

No symptom

33

5.5%

29

4.8%

62

10.3%

240

40.0%

Significant improvement

8

1.3%

9

1.5%

5

0.8%

6

1.0%

Slight improvement

362

60.3%

341

56.8%

338

56.3%

131

21.8%

No difference

197

32.8%

221

36.8%

195

32.5%

223

37.2%

12 h (n=400)a

No symptom

51

12.8%

102

25.5%

83

20.8%

121

30.3%

Significant improvement

0

0.0%

0

0.0%

1

0.3%

0

0.0%

Slight improvement

4

1.0%

24

6.0%

105

26.3%

140

35.0%

No difference

345

86.3%

274

68.5%

211

52.8%

139

34.8%

Measurement

Improvement

Stool Frequency

Stool Consistency

All Symptoms

  
  

n

%

n

%

n

%

  

1 h (n=600)

No symptom

120

20.0%

128

21.3%

16

2.7%

  

Significant improvement

1

0.2%

1

0.2%

282

47.0%

  

Slight improvement

65

10.8%

61

10.2%

236

39.3%

  

No difference

414

69.0%

410

68.3%

66

11.0%

  

3 h (n=600)

No symptom

304

50.7%

310

51.7%

4

0.7%

  

Significant improvement

0

0.0%

1

0.2%

480

80.0%

  

Slight improvement

114

19.0%

87

14.5%

100

16.7%

  

No difference

182

30.3%

202

33.7%

16

2.7%

  

12 h (n=400)a

No symptom

199

49.8%

202

50.5%

21

5.3%

  

Significant improvement

0

0.0%

0

0.0%

127

31.8%

  

Slight improvement

25

6.3%

22

5.5%

186

46.5%

  

No difference

176

44.0%

176

44.0%

66

16.5%

  
  1. aThe VAS was not assessed at 12 h in Shanghai