The effect of weight loss on HDL subfractions and LCAT activity in two genotypes of APOA-II -265T>C polymorphism

Nutrition Journal

Table 1 General characteristic of −265 T>C polymorphism subjects at the baseline

Variable	TT/TC (n = 22)	CC (n = 22)	P _value
BMI(kg/m²)
Overweight	10(45.5)	10(45.5)	0.67^a
Obese	12(55.5)	12(55.5)	0.67^a
Waist/Hip	0.96(0.04)	0.97(0.06)	0.72^b
APOA-II/APOA-I	1.49(0.11)	1.44(0.36)	0.60^b
HDL(ng/ml)	43.63(8.16)	46.18(7.79)	0.29^b
HDL2(ng/ml)	16.08(0.3)	14.72(0.29)	0.33^b
HDL3(ng/ml)	28.04(0.24)	31.99(0.32)	0.13^b
LCAT activity(470/390)	0.22(0.07)	0.23(0.08)	0.60^b

Values are presented as mean ± standard deviation for continuous and number (%) for categorical variables
BMI Body Mass Index, APOA-I Apolipoprotein A-I, APOA-II Apolipoprotein A-II, HDL High Density Lipoprotein, LCAT Lecithin: cholesterol acyltransferase
For HDL2 and HDL3 Geometric Mean Ratio was used
^aUsing the chi-square test ^bUsing independent sample t-test^,
P _value ≤0/05 was considered as statistically significant

ISSN: 1475-2891