Skip to main content

Table 4 Odds ratio (OR) and 95% confidence intervals (CIs) for neurodevelopment indices of BSID-II (each score below 85a) according to maternal fatty acids ratio

From: Association between maternal intake of n-6 to n-3 fatty acid ratio during pregnancy and infant neurodevelopment at 6 months of age: results of the MOCEH cohort study

  

MDI

PDI

Range

No. of delayed performance

OR (95% CI)

No. of delayed performance

OR (95% CI)

Model 1

Model 2

Model 3

Model 1

Model 2

Model 3

n-6/n-3 PUFAs

 Quartile 1

0.13-7.00

31 (12.9)b

1 (ref)

1 (ref)

1 (ref)

40 (16.7)

1 (ref)

1 (ref)

1 (ref)

 Quartile 2

7.01-9.04

32 (13.3)

1.037 (0.611-1.762)

1.000 (0.507-1.975)

1.067 (0.477-2.384)

48 (20.0)

1.250 (0.786-1.988)

1.114 (0.619-2.002)

1.489 (0.735-3.014)

 Quartile 3

9.05-11.66

35 (14.6)

1.151 (0.684-1.937)

1.468 (0.756-2.848)

1.769 (0.819-3.823)

48 (20.0)

1.250 (0.786-1.988)

1.484 (0.830-2.654)

1.819 (0.907-3.649)

 Quartile 4

11.68-108.24

40 (16.7)

1.348 (0.812-2.240)

1.538 (0.806-2.936)

2.156 (1.025-4.535)

53 (22.1)

1.417 (0.898-2.237)

1.339 (0.752-2.385)

1.651 (0.820-3.321)

LA/ALA

 Quartile 1

0.13-8.20

25 (10.4)

1 (ref)

1 (ref)

1 (ref)

36 (15.0)

1(ref)

1 (ref)

1 (ref)

 Quartile 2

8.21-9.69

35 (14.6)

1.468 (0.849-2.539)

1.620 (0.814-3.227)

1.507 (0.667-3.408)

52 (21.7)

1.567 (0.980-2.504)

2.111 (1.154-3.862)

2.965 (1.376-6.390)

 Quartile 3

9.70-12.47

41 (17.1)

1.772 (1.039-3.021)

1.808 (0.901-3.626)

1.958 (0.867-4.423)

50 (20.8)

1.491 (0.930-2.389)

1.909 (1.016-3.588)

3.047 (1.374-6.756)

 Quartile 4

12.48-108.24

37 (15.4)

1.567 (0.911-2.696)

1.707 (0.858-3.393)

2.284 (1.042-5.009)

51 (21.3)

1.529 (0.955-2.446)

1.770 (0.954-3.285)

2.551 (1.160-5.607)

  1. BSID-II Bayley Scales of Infant Development II MDI mental development index PDI psychomotor development index PUFAs polyunsaturated fatty acids, LA linoleic acid AA arachidonic acid ALA α-linolenic acid, EPA eicosapentanoic acid DHA docosahexaenoic acid
  2. aMDI and PDI can be categorized into four groups such as ‘significantly delayed performance (below 70)’, ‘mildly delayed performance (70–84)’, ‘within normal limits (85–114)’, and ‘accelerated performance (above 114)’
  3. bValues are expressed as frequency (%)
  4. Model 1: Unadjusted
  5. Model 2: Adjusted for maternal age, pre-pregnancy BMI, urinary cotinine level (log-transformed), residential area, maternal education level, use of supplements, maternal energy intake (log-transformed), gestational age, infant gender, breastfeeding status and infantile polyunsaturated fatty acid intake (log-transformed)
  6. Model 3: Additionally adjusted for cord blood mercury level (log-transformed)
Back to article page

Nutrition Journal

ISSN: 1475-2891

Contact us