|
Placebo (n = 19)
|
Q10-300 (n = 20)
|
---|
males (n, %)
|
12 (63.2 %)
|
15 (75.0 %)
|
age (y)
|
61.5 ± 11.0 (62.0)a
|
59.7 ± 8.3 (58.5)
|
SBP (mmHg)
|
133.8 ± 18.0 (134.0)
|
124.8 ± 19.3 (119.5)
|
DBP (mmHg)
|
77.9 ± 11.2 (78.0)
|
76.9 ± 12.3 (76.0)
|
waist circumference (cm)
|
89.1 ± 7.8 (88.0)
|
86.7 ± 10.2 (88.5)
|
waist hip ratio
|
0.92 ± 0.05 (0.91)
|
0.94 ± 0.16 (0.94)
|
BMI (kg/m2)
|
24.7 ± 3.2 (24.5)
|
23.1 ± 2.6 (22.8)
|
current smokerb, n (%)
|
6 (31.6 %)
|
5 (25.0 %)
|
drinks alcoholc, n (%)
|
3 (15.8 %)
|
3 (15.0 %)
|
Exercised, n (%)
|
9 (47.4 %)
|
8 (40.0 %)
|
Hepatitis B, n (%)
|
14 (73.7 %)
|
12 (60.0 %)
|
Hepatitis C, n (%)
|
4 (21.1 %)
|
7 (35.0 %)
|
Cirrhosis, n (%)
|
6 (31.6 %)
|
5 (25.0 %)
|
Recurrence, n (%)
|
3 (15.8 %)
|
4 (20.0 %)
|
Hematology
|
BUN (mg/dL)
|
15.5 ± 4.9 (15.0)
|
17.1 ± 9.2 (15.5)
|
creatinine (mg/dL)
|
0.8 ± 0.3 (0.8)
|
0.9 ± 0.3 (0.9)
|
GOT (IU/L)
|
35.2 ± 24.8 (27.0)
|
40.4 ± 23.0 (31.5)
|
GPT (IU/L)
|
44.8 ± 36.6 (38.0)
|
55.5 ± 39.8 (45.5)
|
TC (mg/dL)
|
162.7 ± 36.4 (148.0)
|
162.1 ± 32.7 (156.0)
|
TG (mg/dL)
|
95.3 ± 42.3 (87.0)
|
93.4 ± 29.9 (92.5)
|
LDL-C (mg/dL)
|
100.4 ± 32.3 (90.0)
|
102.3 ± 32.8 (100.0)
|
HDL-C (mg/dL)
|
50.6 ± 11.6 (50.0)
|
49.2 ± 12.4 (47.5)
|
TC / HDL-C
|
3.3 ± 1.0 (2.9)
|
3.5 ± 1.0 (3.5)
|
Dietary intake
|
Energy (kcal/d)
|
1608.5 ± 334.5 (1531.2)
|
1686.5 ± 460.8 (1655.8)
|
Protein (g/d)
|
65.9 ± 17.9 (68.0)
|
66.2 ± 21.2 (66.8)
|
% of total calories
|
16.6 %
|
15.7 %
|
Fat (g/d)
|
49.5 ± 23.9 (48.2)
|
50.6 ± 16.1 (51.7)
|
% of total calories
|
26.6 %
|
26.8 %
|
carbohydrate (g/d)
|
228.6 ± 40.8 (227.0)
|
251.1 ± 89.6 (238.6)
|
% of total calories
|
57.2 %
|
57.9 %
|
PUFA (g/d)
|
15.6 ± 11.8 (13.0)
|
13.8 ± 8.6 (11.1)
|
MUFA (g/d)
|
15.1 ± 9.5 (11.9)
|
15.3 ± 6.6 (15.6)
|
SFA (g/d)
|
12.8 ± 8.0 (10.3)
|
14.2 ± 5.7 (14.3)
|
vitamin A (μg R.E./d)
|
3216.8 ± 4244.7 (1188.1)
|
3204.2 ± 3705.5 (1110.4)
|
vitamin E (mg α-T.E./d)
|
421.6 ± 727.1 (21.5)
|
615.0 ± 989.3 (10.8)
|
cholesterol (mg/d)
|
250.0 ± 163.8 (238.2)
|
231.8 ± 117.6 (197.8)
|
dietary fiber (g/d)
|
13.0 ± 6.5 (11.9)
|
10.9 ± 6.1 (9.7)
|
- BMI body mass index, BUN blood urea nitrogen, GOT glutamic oxaloacetic transaminase, HCC hepatocellular carcinoma, HDL-C high-density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, MUFA monounsaturated fatty acid, PUFA polyunsaturated fatty fat, SFA saturated fatty acid, TC total cholesterol, TG triglyceride
- ameans ± SD (medians)
- bcurrent smoker: individuals currently smoking one or more cigarettes per day
- cdrinks alcohol: individuals drinking one or 1 more alcoholic drinks per day regularly
- dexercise: individuals who exercise regularly at least 3 times every week