Appropriate vitamin D loading regimen for patients with advanced lung cancer

Nutrition Journal

Table 2 Baseline characteristics

Variable	Initial study group (n = 91)	Study completed group (n = 80)
Age (y)	63.0 ± 11.2	63.3 ± 11.4
Male sex (%)	49	51
Smoker (%)	32	33
Weight loss history (%)	52	51
Body weight (kg)	71.9 ± 14.6	72.6 ± 14.9
BMI (kg/m²)	26.1 ± 4.4	26.1 ± 4.6
Blood hemoglobin (g/L)	121 ± 19	121 ± 19
Serum albumin (g/L)	39 ± 4	39 ± 4
Plasma 25(OH)D (nmol/L)	47.6 ± 28.1	48.2 ± 28.3
Subnormal (%)	85	84
Deficient (%)	26	25
Plasma total vitamin C (μmol/L)	41.5 ± 27.6	42.5 ± 27.5
Subnormal (%)	41	40
Plasma vit D binding protein (μg/mL)	228 ± 63	230 ± 64
Serum calcium (mmol/L)	2.34 ± 0.10	2.33 ± 0.09
Plasma parathyroid hormone (ng/L)	48.8 ± 25.1	48.7 ± 23.7
Plasma C-reactive protein (mg/L)	21.3 ± 38.0	20.9 ± 36.8
Total mood disturbance score	10.7 ± 17.9	10.0 ± 17.1
Distress Thermometer score	2.1 ± 2.6	1.9 ± 2.2
ESAS-r	20.6 ± 14.4	20.3 ± 14.0

Data are presented as mean ± SD. Reference intervals are as follows: hemoglobin (men 140–175 g/L, women 120–152 g/L), albumin (35–51 g/L), C-reactive protein (<10 mg/L), parathyroid hormone (10–70 ng/L), calcium (2.12–2.62 mmol/L), total vitamin C (>28.3 μmol/L), 25(OH)D (75–250 nmol/L) and deficient level (<25 nmol/L), vitamin D binding protein (43–415 μg/mL). The total mood disturbance score ranges from −20 to 100, the Distress Thermometer score ranges from 0 to 10. and the ESAS-r (revised Edmonton Symptom Assessment System) ranges from 0 to 100
Percent smoker includes individuals who quit less than 1 year before enrollment
Percent weight loss history refers to a history of involuntary weight loss at onset of study

ISSN: 1475-2891