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Table 3 Biochemistry and haematology values between two treatment groups

From: Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study

Lab parameter (Units) Visit Placebo Active Normal range
Alanine aminotransferase (IU L−1) Baseline 23.5 ± 6.44 22.8 ± 5.64 0 to 41
Final Visit 23.4 ± 4.81 28.4 ± 11.20
Albumin (g dL−1) Baseline 4.2 ± 0.36 4.2 ± 0.70 3.5 to 5.2
Final Visit 4.4 ± 0.28 4.1 ± 0.45
Alkaline phosphatase (U L−1) Baseline 76.6 ± 8.73 86.0 ± 5.98 53 to 128
Final Visit 75.9 ± 8.76 82.8 ± 3.44
Aspartate aminotransferase (IU L−1) Baseline 24.9 ± 5.79 25.1 ± 5.63 0 to 40
Final Visit 24.9 ± 6.56 27.4 ± 8.47
Blood urea nitrogen (mg dL−1) Baseline 12.3 ± 3.38 10.7 ± 1.66 5.0 to 24
Final Visit 11.1 ± 2.69 10.9 ± 1.85
Fasting blood sugar (mg dL−1) Baseline 99.1 ± 2.54 106.2 ± 3.89 70 to 110
Final Visit 104.2 ± 2.99 120.4 ± 9.48
LDL Cholesterol (mg dL−1) Baseline 105.4 ± 5.08 109.2 ± 5.69 Up to 140
Final Visit 110.1 ± 4.30 91.3 ± 3.92
Potassium (mEq L−1) Baseline 4.1 ± 0.19 4.1 ± 0.33 3.5 to 5.2
Final Visit 4.2 ± 0.18 4.1 ± 0.34
Serum creatinine (mg %) Baseline 0.9 ± 0.12 0.9 ± 0.13 0.6 to 1.4
Final Visit 0.9 ± 0.09 0.9 ± 0.15
Sodium (mEq L−1) Baseline 139.8 ± 1.76 139.3 ± 3.30 136 to 145
Final Visit 140.7 ± 2.58 139.6 ± 4.36
Total bilirubin (mg dL−1) Baseline 1.2 ± 1.54 0.8 ± 0.27 0.1 to 1.2
Final Visit 0.8 ± 0.23 0.8 ± 0.23
Total protein (g dL−1) Baseline 7.1 ± 0.56 7.2 ± 0.34 6.22 to 8.0
Final Visit 7.5 ± 0.31 7.3 ± 0.50
Erythrocyte Count (*106 cells) Baseline 4.9 ± 0.78 5.0 ± 0.53 4.0 to 6.5
Final Visit 4.5 ± 0.70 4.6 ± 0.61
Haematocrit (%) Baseline 40 ± 0.06 40 ± 0.05 40 to 50
Final Visit 40 ± 0.06 40 ± 0.06
Haemoglobin (gm %) Baseline 12.8 ± 2.77 12.9 ± 1.87 11 to 16
Final Visit 13.8 ± 2.31 13.0 ± 2.39
Leukocyte Count (Cells cu. mm−1) Baseline 6383.3 ± 16.92 6309.4 ± 16.32 4000 to 11,000
Final Visit 7328.6 ± 18.95 6788.2 ± 16.74
Lymphocytes (%) Baseline 30 ± 0.06 31 ± 0.06 25 to 40
Final Visit 30 ± 0.06 30 ± 0.06
Monocytes (%) Baseline 0.0 ± 0.01 0.0 ± 0.02 0 to 10
Final Visit 0.0 ± 0.01 0.0 ± 0.01
Neutrophils (%) Baseline 60 ± 0.05 60 ± 0.06 40 to 75
Final Visit 60 ± 0.06 60 ± 0.07
Basophils (%) Baseline 0.0 ± 0.00 0.0 ± 0.00 0 to 1
Final Visit 0.0 ± 0.00 0.0 ± 0.00
Eosinpophils (%) Baseline 0.0 ± 0.01 0.0 ± 0.01 0 to 7
Final Visit 0.0 ± 0.01 0.0 ± 0.01
Platelet Count (*105 per cu. mm) Baseline 2.9 ± 0.67 2.7 ± 0.72 1.5 to 4.5
  Final Visit 3.2 ± 0.78 3.0 ± 0.66
  1. Values expressed as mean ± S.D