Safety and efficacy of an olive oil-based triple-chamber bag for parenteral nutrition: a prospective, randomized, multi-center clinical trial in China

Table 2 Effects of OLIVE and SOYBEAN on Markers of Nutrition in Patients Receiving Parenteral Nutrition

Nutrition Marker		OLIVE		SOYBEAN		OLIVE vs SOYBEAN
	Visit	N	Mean ± SD	N	Mean ± SD	LSGM Ratio (95 % CI)	P-value
Albumin (g/L)	Baseline	214	33.11 ± 5.75	220	33.23 ± 5.84		.
	Day 5	211	34.02 ± 5.32	216	32.93 ± 5.15	1.04 (1.01, 1.07)	0.0139
	EOT/Day 14	82	35.37 ± 5.86	78	35.55 ± 5.3	1 (0.96, 1.05)	0.9393
Prealbumin (mg/dL)	Baseline	213	15.08 ± 4.64	219	15.15 ± 5.01		.
	Day 5	217	15.66 ± 5.12	218	13.95 ± 5.05	1.12 (1.06, 1.19)	0.0002
	EOT/Day 14	210	17.24 ± 6.82	219	15.15 ± 6.37	1.16 (1.08, 1.24)	0.0001
Prealbumin (PP) (mg/dL)	Baseline	182	14.82 ± 4.58	188	14.97 ± 5.02		.
	Day 5	184	15.7 ± 5.01	190	14.19 ± 5.06	1.12 (1.05, 1.19)	0.0006
	EOT/Day 14	184	17.38 ± 6.96	193	15.37 ± 6.43	1.16 (1.07, 1.25)	0.0002
IGF-I (ug/L)	Baseline	214	107.31 ± 49.61	220	110.9 ± 55.34		.
	Day 5	211	125.81 ± 64.35	218	121.15 ± 61.11	1.04 (0.96, 1.13)	0.3437
	EOT/Day 14	82	142.9 ± 70.16	78	125.27 ± 65.22	1.16 (1, 1.35)	0.045
6-h urea nitrogen, urine (mmol/L)	Baseline	211	124.02 ± 92.1	218	129.39 ± 78.47		.
	Day 5	211	141.95 ± 100.85	216	151.82 ± 98.15	0.91 (0.8, 1.03)	0.1271
	EOT/Day 14	81	150.4 ± 100.19	76	144 ± 101.81	1 (0.82, 1.23)	0.9797
6-h 3-Methylthistidine, urine (ug/mL)	Baseline	211	1.32 ± 2.61	217	1.37 ± 1.56		.
	Day 5	212	1.44 ± 4.29	216	1.11 ± 0.98	1.02 (0.9, 1.14)	0.7791
	EOT/Day 14	81	1.98 ± 2.18	77	1.74 ± 4.4	1.1 (0.87, 1.38)	0.4224

Abbreviations: CI confidence interval, EOT end of therapy, IGF-I insulin-like growth factor-I, LSGM least square geometric mean, PP per protocol, SD standard deviation

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