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Table 1 Summary of clinical trials using cinnamon and their outcomes

From: The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials

  Study design Duration Type of cinnamon & dose/day FPG HbA1C
  Baseline mean ± SD Post intervention mean ± SD Baseline Mean ± SD Post intervention ± SD
1 Khan et al [58] Single-blind RCT 40 days intervention 20 days washout C.cassia powder 1 g,3 g,6 g Placebo 13.77 ± 1.33 13.97 ± 1.23 _ _
Cinnamon 12.0 ± 1.43 9.1 ± 1.40 _ _
2 Mang et al [72] Double- blind RCT 40 days C.cassia aqueous extract 3 g Placebo 8.66 ± 1.47 8.31 ± 1.62 6.71 ± 0.73 6.68 ± 0.7
Cinnamon 9.26 ± 2.26 8.15 ± 1.65 6.86 ± 1.00 6.83 ± 0.83
3 Suppapitiporn et al [54] Single blind RCT 12 weeks C.cassia powder 1.5 g Placebo _ _ 8.14 7.76
Cinnamon _ _ 8.06 7.87
4 Vanschoonbe et al [55] Double-blind RCT 6 weeks C.cassia powder 1.5 g Placebo 8.28 ± 0.33 8.07 ± 0.36 7.1 ± 0.2 7.2 ± 0.2
Cinnamon 8.37 ± 0.64 7.91 ± 0.71 7.4 ± 0.3 7.5 ± 0.3
5 Blevins et al [56] Double-blind RCT 3 months C.cassia powder 1 g Placebo 8.04 8.02 7.1 7.2
Cinnamon 7.38 6.84 7.2 7.4
6 Crawford [57] Randomized placebo controlled trial (no blind/open) 90 days C.cassia powder 1 g Placebo _ _ 8.28 ± 1.3 7.91 ± 1.5
Cinnamon _ _ 8.47 ± 1.8 7.64 ± 1.7
7 Akilen et al [60] Double-blind RCT 12 weeks C.cassia powder 2 g Placebo 8.77 ± 2.59 8.74 ± 3.11 8.55 ± 1.82 8.68 ± 1.83
Cinnamon 8.82 ± 3.45 8.04 ± 3.10 8.22 ± 1.16 7.86 ± 1.42
8 Anderson et al [20] Randomized placebo controlled trial 2 months C.cassia(CinSulin) 500 mg Placebo 8.57 ± 0.32 8.44 ± 0.34 _ _
Cinnamon 8.85 ± 0.36 8.19 ± 0.29 _ _