The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials

Medagama, Arjuna B.

doi:10.1186/s12937-015-0098-9

Nutrition Journal

Table 1 Summary of clinical trials using cinnamon and their outcomes

From: The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials

		Study design	Duration	Type of cinnamon & dose/day		FPG		HbA₁C
		Study design	Duration			Baseline mean ± SD	Post intervention mean ± SD	Baseline Mean ± SD	Post intervention ± SD
1	Khan et al [58]	Single-blind RCT	40 days intervention 20 days washout	C.cassia powder 1 g,3 g,6 g	Placebo	13.77 ± 1.33	13.97 ± 1.23	_	_
1	Khan et al [58]	Single-blind RCT	40 days intervention 20 days washout	C.cassia powder 1 g,3 g,6 g	Cinnamon	12.0 ± 1.43	9.1 ± 1.40	_	_
2	Mang et al [72]	Double- blind RCT	40 days	C.cassia aqueous extract 3 g	Placebo	8.66 ± 1.47	8.31 ± 1.62	6.71 ± 0.73	6.68 ± 0.7
2	Mang et al [72]	Double- blind RCT	40 days	C.cassia aqueous extract 3 g	Cinnamon	9.26 ± 2.26	8.15 ± 1.65	6.86 ± 1.00	6.83 ± 0.83
3	Suppapitiporn et al [54]	Single blind RCT	12 weeks	C.cassia powder 1.5 g	Placebo	_	_	8.14	7.76
3	Suppapitiporn et al [54]	Single blind RCT	12 weeks	C.cassia powder 1.5 g	Cinnamon	_	_	8.06	7.87
4	Vanschoonbe et al [55]	Double-blind RCT	6 weeks	C.cassia powder 1.5 g	Placebo	8.28 ± 0.33	8.07 ± 0.36	7.1 ± 0.2	7.2 ± 0.2
4	Vanschoonbe et al [55]	Double-blind RCT	6 weeks	C.cassia powder 1.5 g	Cinnamon	8.37 ± 0.64	7.91 ± 0.71	7.4 ± 0.3	7.5 ± 0.3
5	Blevins et al [56]	Double-blind RCT	3 months	C.cassia powder 1 g	Placebo	8.04	8.02	7.1	7.2
5	Blevins et al [56]	Double-blind RCT	3 months	C.cassia powder 1 g	Cinnamon	7.38	6.84	7.2	7.4
6	Crawford [57]	Randomized placebo controlled trial (no blind/open)	90 days	C.cassia powder 1 g	Placebo	_	_	8.28 ± 1.3	7.91 ± 1.5
6	Crawford [57]	Randomized placebo controlled trial (no blind/open)	90 days	C.cassia powder 1 g	Cinnamon	_	_	8.47 ± 1.8	7.64 ± 1.7
7	Akilen et al [60]	Double-blind RCT	12 weeks	C.cassia powder 2 g	Placebo	8.77 ± 2.59	8.74 ± 3.11	8.55 ± 1.82	8.68 ± 1.83
7	Akilen et al [60]	Double-blind RCT	12 weeks	C.cassia powder 2 g	Cinnamon	8.82 ± 3.45	8.04 ± 3.10	8.22 ± 1.16	7.86 ± 1.42
8	Anderson et al [20]	Randomized placebo controlled trial	2 months	C.cassia(CinSulin) 500 mg	Placebo	8.57 ± 0.32	8.44 ± 0.34	_	_
8	Anderson et al [20]	Randomized placebo controlled trial	2 months	C.cassia(CinSulin) 500 mg	Cinnamon	8.85 ± 0.36	8.19 ± 0.29	_	_

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