Impact of daily supplementation of Spirulina platensis on the immune system of naïve HIV-1 patients in Cameroon: a 12-months single blind, randomized, multicenter trial

Table 2 Demographic and clinical characteristics of patients during the trial

Variables	Ctrl/Spi	Period	Patients received local balance diet	Patients received spirulina combined with a local balance diet	p-value
Age (Years)	87/82	T0	35.43 ± 10.04	36.01 ± 9.44	0.58
Sex (%)
Female	87/82	T0	64.5 % (56)	69.8 % (60)	0.06
Male	87/82	T0	35.6 % (31)	25.6 % (22)	0.06
BMI (kg/m²)	87/82	T0	26.02 ± 4.97	25.29 ± 4.54	0 .33
	79/80	T6	25.18 ± 6.41	25.41 ± 4.98	0.80
	66 /79	T12	22.18 ± 1.07	23.26 ± 6.53	0.44
CD4 (cells/μL)	87/82	T0	569.40 ± 179.89	596.32 ± 198	0.36
	79/80	T6	464.86 ± 200.33	609.07 ± 149.14	<0.00*
	66/79	T12	429.04 ± 177.19	614.92 ± 179.43	<0.00*
Viral load (copies/mL)	87/82	T0	61199.03 ± 6.27	74770.33 ± 3.19	0.53
	79/80	T6	66615,45 ± 7.45	38539.70 ± 2.22	<0.00
	66/79	T12	174595.22 ± 1.20	30872.33 ± 3.93	<0.00
Hemoglobin (mg/dL)	87/82	T0	12.87 ± 1.53	13.14 ± 1.85	0.32
	79/80	T6	12.22 ± 1.42	13.49 ± 1.24	<0.00
	66/79	T12	11.69 ± 1.62	12.71 ± 1.71	<0.00
Fasting Blood Sugar (mg/L)	87/82	T0	115 ± 53.70	105.89 ± 25.91	0.159
	79/80	T6	105.00 ± 30.76	103.14 ± 15.93	0.65
	66 /79	T12	113.77 ± 61.85	95.35 ± 9.63	<0.00*

Mean values ± SD. *Significant difference between the group (P < 0.00). Significant difference between the group (p < 0.05). Ctrl: Control, Spi: Spirulina group; To, T6,T13: time (months)

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