Table 1 The clinical characteristics of the study population
From: Relationship of vitamin D status and bone mass according to vitamin D-binding protein genotypes
Total (n = 1,734) | Male ( n = 1,246) | Female ( n = 488) | p value (male vs. female) | |
|---|---|---|---|---|
Age (years) | 39.87 ± 6.65 | 40.07 ± 6.80 | 39.35 ± 6.23 | <0.01 |
BW (kg) | 66.42 ± 12.93 | 70.68 ± 11.38 | 55.55 ± 9.92 | <0.001 |
BMI (kg/m2) | 23.94 ± 3.76 | 24.59 ± 3.54 | 22.27 ± 3.80 | <0.001 |
Waist circumference (cm) | 86.11 ± 10.46 | 89.09 ± 9.42 | 78.51 ± 9.08 | <0.001 |
Waist–hip ratio | 0.88 ± 0.06 | 0.90 ± 0.05 | 0.82 ± 0.06 | <0.001 |
Lumbar spine (L1–L4) BMD (g/m2) | 0.98 ± 0.12 | 0.98 ± 0.12 | 0.98 ± 0.10 | NS |
Femoral neck BMD (g/m2) | 0.80 ± 0.12 | 0.82 ± 0.12 | 0.75 ± 0.10 | <0.001 |
Total hip BMD (g/m2) | 0.92 ± 0.15 | 0.95 ± 0.14 | 0.86 ± 0.15 | <0.001 |
Serum P1NP (ng/mL) | 46.28 ± 18.02 | 48.55 ± 18.48 | 40.48 ± 15.35 | <0.001 |
Serum CTx-I (ng/mL) | 0.35 ± 0.16 | 0.39 ± 0.16 | 0.25 ± 0.12 | <0.001 |
Total 25(OH)D (nmol/L) | 61.95 ± 15.17 | 65.20 ± 14.74 | 53.64 ± 12.90 | <0.001 |
Subgroup stratified by 25(OH)D levels | ||||
<50 nmol/L | 42.93 ± 5.82 (n = 371) | 44.14 ± 4.40 (n = 169) | 41.92 ± 6.63 (n = 202) | <0.001 |
50 to < 75 nmol/L | 61.68 ± 6.67 (n = 1,051) | 62.28 ± 6.61 (n = 790) | 59.87 ± 6.55 (n = 261) | <0.001 |
≥75 nmol/L | 85.45 ± 10.25 (n = 312) | 85.64 ± 10.46 (n = 287) | 83.26 ± 7.23 (n = 25) | NS |
Fetuin-A (μg/mL) | 559.16 ± 110.64 | 560.87 ± 110.29 | 554.79 ± 111.53 | NS |