The mechanism by which moderate alcohol consumption influences coronary heart disease

Nutrition Journal

Table 2 Putative effects of high-glycemic load diets and salient CHD pathogenetic pathways

Lifestyle	Pathways, and pathway numbers corresponding to those in Figure 1	Refs.
Moderate alcohol consumption	a. 1-12-↓ LDL-33-51-↓ hypercholesterolaemia	a. [3,7,8,25,26,153]
	b. 1-10-↑ HDL-31-↓ hypercholesterolaemia	b. [3,7,8,25,26,153]
	c. 1-14-↓ blood glucose-55-↓ hyperglycaemia	c. [3,7,8,25,26,153]
	d. 1-14-↓ blood glucose-54-69-↓ insulin resistance-70-89-↓ hypertension-100-↓ ROS-85-↓ inflammatory state	d. [28,153]
	e. 1-14-↓ blood glucose-54-69-↓ insulin resistance-72-↑ vasodilation	e. [128]

↑ denotes up regulation/increase, ↓ denotes down regulation/decrease, x-y-z indicates pathway connecting x to y to z. HDL, high-density lipoprotein; LDL, low-density lipoprotein; ROS, reactive oxygen species.

ISSN: 1475-2891