Table 4 Baseline and delta values in those who completed the study

N

110

97

105

Males (%)

40.0

40.2

39.0

Age (years)

47.3 ± 11.1

47.7 ± 11.6

50.8 ± 10.7

BMI (kg/m²)

34.4 ± 3.9

33.7 ± 3.5*

35.2 ± 3.9

0.01 ± 1.33

0.13 ± 1.10

0.09 ± 1.35

Smokers (%)

20.9

20.6

17.1

BMD L2-L4 (g/cm²)

1.270 ± 0.155

1.235 ± 0.161

1.251 ± 0.170

0.008 ± 0.036

0.008 ± 0.039

0.007 ± 0.042

BMD total hip (g/cm²)

1.107 ± 0.133

1.067 ± 0.128

1.092 ± 0.130

0.008 ± 0.014

0.011 ± 0.014

0.009 ± 0.017

OPG (pg/ml)

1875 ± 509

1961 ± 600

2092 ± 650

56 ± 306¹

- 34 ± 472²

RANKL (pg/ml)

0.09 ± 0.15

0.10 ± 0.27

0.05 ± 0.10

- 0.01 ± 0.10¹

0.00 ± 0.06²

Serum 25(OH)D (nmol/L)

61.3 ± 20.7

58.3 ± 21.2

60.1 ± 22.3

79.9 ± 31.3^†

41.7 ± 22.8^†

- 2.2 ± 16.8

Serum PTH (pmol/L)

5.1 ± 1.6

5.4 ± 1.8

5.7 ± 1.7

- 0.9 ± 1.5^†

- 0.7 ± 1.4*

- 0.2 ± 1.6

Serum calcium (mmol/L)

2.30 ± 0.11

2.32 ± 0.11

2.31 ± 0.10

- 0.01 ± 0.12

- 0.02 ± 0.12

- 0.01 ± 0.11