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Table 4 Baseline and delta values in those who completed the study

From: No significant effect on bone mineral density by high doses of vitamin D3 given to overweight subjects for one year

 

Baseline values

Delta values (value at end of study minus baseline)

 

DD group

DP group

PP group

DD group

DP group

PP group

N

110

97

105

   

Males (%)

40.0

40.2

39.0

   

Age (years)

47.3 ± 11.1

47.7 ± 11.6

50.8 ± 10.7

   

BMI (kg/m2)

34.4 ± 3.9

33.7 ± 3.5*

35.2 ± 3.9

0.01 ± 1.33

0.13 ± 1.10

0.09 ± 1.35

Smokers (%)

20.9

20.6

17.1

   

BMD L2-L4 (g/cm2)

1.270 ± 0.155

1.235 ± 0.161

1.251 ± 0.170

0.008 ± 0.036

0.008 ± 0.039

0.007 ± 0.042

BMD total hip (g/cm2)

1.107 ± 0.133

1.067 ± 0.128

1.092 ± 0.130

0.008 ± 0.014

0.011 ± 0.014

0.009 ± 0.017

OPG (pg/ml)

1875 ± 509

1961 ± 600

2092 ± 650

56 ± 3061

 

- 34 ± 4722

RANKL (pg/ml)

0.09 ± 0.15

0.10 ± 0.27

0.05 ± 0.10

- 0.01 ± 0.101

 

0.00 ± 0.062

Serum 25(OH)D (nmol/L)

61.3 ± 20.7

58.3 ± 21.2

60.1 ± 22.3

79.9 ± 31.3†

41.7 ± 22.8†

- 2.2 ± 16.8

Serum PTH (pmol/L)

5.1 ± 1.6

5.4 ± 1.8

5.7 ± 1.7

- 0.9 ± 1.5†

- 0.7 ± 1.4*

- 0.2 ± 1.6

Serum calcium (mmol/L)

2.30 ± 0.11

2.32 ± 0.11

2.31 ± 0.10

- 0.01 ± 0.12

- 0.02 ± 0.12

- 0.01 ± 0.11

  1. *P < 0.05; † P < 0.001 versus delta values in the PP grooup
  2. 1N = 76; 2N = 81