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Table 1 Baseline characteristics of the study subjects

From: Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint®) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial

Variable Study group P value
  Hyal-Joint® (n = 11) Placebo (n = 9)  
Men/women 4/7 5/4 0.653
Age, years, mean (SD) 57.7 (10.1) 54.6 (7.7) 0.448
Ethnicity    0.361
   Black 0 1  
   Caucasian 1 1  
   Hispanic 10 6  
Height, cm, mean (SD) 164.7 (6.1) 164.1 (10.8) 0.889
Weight, kg, mean (SD 79.1 (26.3) 80.9 (20.7) 0.867
Heart rate, beats/min, mean (SD) 75.5 (12.3) 75.7 (12.4) 0.970
Systolic BP, mm Hg, mean (SD) 122.8 (16.4) 135.6 (21.7) 0.152
Diastolic BP, mm Hg, mean (SD) 77.8 (8.9) 84.3 (10.4) 0.148
Rescue medication use (paracetamol 500 mg)*    
   No. capsules (range) 4 (0–19) 9 (0–29) 0.425
   Mean (SD) 6.8 (7.3) 9.9 (9.6)  
WOMAC scores, mean (SD)    
   Pain 10.4 (3.0) 10.1 (2.7) 0.848
   Stiffness 4.4 (1.0) 4.4 (1.0) 0.862
   Physical function 37.7 (7.4) 35.4 (11.5) 0.597
   Aggregated total symptoms 52.5 (10.8) 50.0 (14.4) 0.667
SF-36v2 scores, mean (SD)    
   Physical functioning 30.8 (8.5) 27.1 (8.5) 0.342
   Role-physical 35.3 (8.3) 41.9 (7.8) 0.084
   Bodily pain 33.2 (4.8) 36.9 (4.8) 0.100
   General health 44.1 (12.3) 45.4 (10.3) 0.814
   Vitality 49.0 (11.3) 50.4 (11.7) 0.791
   Social functioning 37.5 (12.0) 43.5 (11.3) 0.268
   Role-emotional 36.1 (12.6) 40.3 (12.9) 0.467
   Mental health 40.3 (19.7) 47.5 (9.5) 0.326
   Physical component summary (PCS-36) 34.8 (6.3) 34.6 (6.4) 0.947
   Mental component summary (MCS-36) 43.6 (17.5) 50.6 (11.2) 0.317
  1. *Between screening and randomization visits.