Skip to main content

Table 3 Antioxidant parameters in healthy volunteers after single ingestion of native or dealcoholized red wine

From: Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial [ISRCTN68505294]

  RW DRW Controls
Parameter    
TPP, mg CE/L    
   Baseline 15.1 ± 2.0 15.9 ± 2.0 13.9 ± 2.8
   90 min 17.7 ± 1.8*a 18.3 ± 2.5* b 14.3 ± 3.5a,b
   360 min 15.5 ± 1.8* 16.6 ± 2.0* 14.3 ± 2.7*
TEAC, mmol/L    
   Baseline 1.22 ± 0.08 1.25 ± 0.08 1.23 ± 0.05
   90 min 1.25 ± 0.07 1.28 ± 0.08 1.26 ± 0.05
   360 min 1.23 ± 0.08 1.24 ± 0.07 1.24 ± 0.04
Vitamin C, mg/dL    
   Baseline 1.33 ± 0.26 1.15 ± 0.18 1.14 ± 0.30
   90 min 1.27 ± 0.21 1.18 ± 0.18 1.17 ± 0.35
   360 min 1.11 ± 0.22* 1.35 ± 0.32* 1.14 ± 0.26
Uric acid, mg/dL    
   Baseline 4.6 ± 1.0 4.8 ± 1.2 4.6 ± 1.1
   90 min 5.3 ± 1.0* 4.9 ± 1.1 4.9 ± 1.2
   360 min 4.5 ± 0.9 4.5 ± 1.0 4.4 ± 1.1
Albumin, g/dL    
   Baseline 4.1 ± 0.4 4.4 ± 0.4 4.1 ± 0.4
   90 min 4.4 ± 0.4 4.4 ± 0.5 4.3 ± 0.3*
   360 min 4.4 ± 0.4 4.4 ± 0.5 4.4 ± 0.5
Bilirubin, mg/dL    
   Baseline 0.73 ± 0.44 0.69 ± 0.27 0.54 ± 0.23
   90 min 0.71 ± 0.37 0.68 ± 0.22 0.61 ± 0.27*
   360 min 0.52 ± 0.29* 0.53 ± 0.26* 0.50 ± 0.22
TM0, arbitrary units    
   Baseline 1,86 ± 0,48 1,98 ± 0,33 2,19 ± 0,67
   90 min 2,03 ± 0,43 2,36 ± 0,23 2,43 ± 0,43
   360 min 2,61 ± 0,43* 2,67 ± 0,24* 2,33 ± 0,44
TM300, arbitrary units    
   Baseline 1,69 ± 0,92 1,43 ± 0,78 1,15 ± 1,07
   90 min 1,39 ± 0,65 1,05 ± 0,87 0,78 ± 1,23
   360 min 1,22 ± 0,67c 0,21 ± 0,45*c,d 1,21 ± 0,52d
  1. Amounts of study drinks ingested were 200 mL red wine (RW), 175 mL dealcoholized red wine (DRW) or 200 mL water (Controls)
  2. TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks);
  3. TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks)
  4. Values are means ± SD, n = 9 for all experiments except for control group at 90 min, n = 7 for all parameters; DRW, n = 8 for TM0, TM300, and control group at 360 min, n = 6 for TM0, TM300
  5. *Values different from baseline, P < 0.05 by Wilcoxon signed rank test
  6. a-dValues marked with identical letters differ between groups, P < 0.05 by Mann-Whitney U-test