|
9
|
Migraine headaches
|
21
|
One initial intramuscular injection (IM) followed by a series of 6 or 8 intravenous (IV) treatments (maximum 50 mg), then regular IM injections (25–50 mg) combined with 50–150 mg of oral administration.
|
17 of the 21 subjects had a positive response.
|
C: case-series
|
|
10
|
Headaches of different etiologic types
|
100
|
100 mg of IV sodium nicotinate or niacin.
|
75 of the 100 subjects had complete relief.
|
C: case-series
|
|
11
|
Migraine headaches
|
15
|
100 mg of IV niacin, and an additional 50–200 mg if necessary to ensure a flushing response of more than 15-minutes.
|
13 of the 15 subjects had a positive response. The headaches were relieved in 27 of the 31 times when niacin was administered by IV administration.
|
C: case-series
|
|
12
|
Tension headaches
|
35
|
22 subjects received 100–200 mg of IV niacin for a total of 53 times.
|
13 of the 22 subjects had a positive response. The headaches were relieved in 41 of the 53 times when niacin was administered by IV administration.
|
C: case-series
|
|
14
|
Emotional or tension headaches
|
5
|
100 mg of IV niacin regularly for 12 weeks combined with a graded schedule of oral dosing, beginning at 300 mg daily, increasing to 900 mg daily, and tapering down to 300 mg daily.
|
All 5 cases of emotional or tension headaches were very responsive to both IV and oral niacin.
|
C: case-series
|
|
15
|
Tension headaches accompanied with depression
|
50
|
100 mg of IV niacin regularly for 23 weeks and then continued once every 2 months and as needed. This was combined with a graded schedule of oral dosing, beginning at 300 mg daily, increasing to 900 mg daily, and tapering down to 300 mg daily.
|
In 44 of the 50 subjects the results with niacin therapy were very satisfactory or favorable.
|
C: case-series
|
|
18
|
Migraine headaches
|
1
|
300–500 mg of niacin were chewed and allowed to slightly dissolve in the mouth.
|
Resolution of migraine headaches.
|
C: case-report
|
|
6
|
Migraine Headaches
|
2
|
500 mg of oral niacin taken at the onset of acute symptoms.
|
In 2 of the 2 subjects, niacin aborted the acute migraine symptoms. In the first subject, niacin resolved the acute attacks in 4 of 4 occasions. In the other subject, niacin resolved the attack on one occasion.
|
C: case-report
|
|
7
|
Migraine headaches
|
1
|
375 mg of oral sustained-release niacin twice daily for 1 month, and 375 mg once daily for 2 months.
|
Migraine-free for the first month, and a marked reduction in migraine headaches over the next 2 months.
|
C: Case-report
|
