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Table 1 Anthropometric, coagulation marker, and plasma vitamin K fraction values at baseline and on Day 36

From: Low-dose menaquinone-4 improves γ-carboxylation of osteocalcin in young males: a non-placebo-controlled dose–response study

 

Units

Baseline

Day 36

Median

Range

Median

Range

Anthropometric data

Age

years

25.00

(20.00-29.00)

-

-

Weight

kg

58.55

(50.55-68.25)

57.95

(50.50-66.90)

BMI

kg/m2

20.60

(18.50-24.10)

20.10

(18.30-23.70)

Coagulation marker

PT-INR

-

1.05

(0.96-1.09)

1.08

(1.03-1.22)*

Plasma vitamin K fraction

Phylloquinone

ng/mL

0.35

(0.22-0.85)

0.20

(0.08-0.49)*

Menaquinone-4

ng/mL

0.14

(0.10-0.17)

0.58

(0.33-1.78)**

Menaquinone-7

ng/mL

0.43

(0.10-7.92)

0.25

(0.13-0.93)

  1. Data are shown as medians with ranges (minimum, maximum) (n=13). Wilcoxon signed-rank test was used to study the effect of MK-4 supplementation on weight, BMI and PT-INR (comparison between baseline and Day 36 values). Plasma vitamin K fraction was analyzed by using Friedman’s test and the post hoc Bonferroni-adjusted Wilcoxon signed-rank test (comparison among baseline and Day 36 values). *P < 0.05, **P < 0.01.