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Table 1 Ascorbic acid intake, anthropometrics, SNP-scores and covariates in MONICA, DCH and INTER99

From: Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts

 

MONICA

DCH

INTER99

N

1,329

2,167

4,073

Basic variables

   

Ascorbic acid (mg/day)

70 (23 to 199)

93 (43 to 207)

66 (25 to 156)

Baseline age (years)

50.5 (30.6 to 61.1)

53.0 (50.0 to 58.0)

45.1 (34.7 to 59.8)

Sex (% women)

51.6

49.4

51.4

Height (cm)

169 (156 to 184)

171 (158 to 186)

172 (158 to 188)

BW (kg)

   

Baseline

69.0 (52.0 to 93.0)

77.1 (56.8 to 104.4)

75.5 (55 to 104)

Follow-up

70.0 (51.6 to 94.7)

82.0 (58.0 to 110.0)

76.5 (55.6 to 105.0)

∆BW

0.22 (−1.04 to 1.61)

1.01 (−1.05 to 2.39)

0.20 (−1.41 to 1.75)

WC (cm) 1

   

Baseline

-

90 (70 to 112)

85 (67 to 107)

Follow-up

-

98 (76 to 121)

88 (69 to 110)

∆WC

-

1.37 (−0.78 to 4.44)

0.55 (−1.27 to 2.46)

SNP-based variables 2

   

SNP-score (BMI)

29 (23 to 35)

28 (23 to 35)

29 (23 to 34)

SNP-score (WC)

3 (1 to 6)

3 (1 to 6)

3 (1 to 6)

SNP-score (WHR)

14 (10 to 18)

14 (10 to 18)

14 (10 to 18)

SNP-score (complete)

44 (37 to 52)

44 (37 to 51)

44 (36 to 51)

Adjustment variables

   

Smoking, % Never smokers

27

41.4

40.1

Education, % ≤ Primary school

35.7

30.1

26.2

Physical activity, % most sedentary group

21.4

9.5

11.5

Menopausal status, % postmenopausal

42.4

55.6

27.5

Total energy intake excl. alcohol, (MJ/day)

8.5 (4.8 to 13.9)

8.2 (4.9 to 13.4)

9.0 (4.9 to 15.1)

Alcohol (MJ/day)

0.4 (0 to 1.8)

0.4 (0 to 1.9)

0.3 (0 to 1.5)

  1. Abbreviations: BW body weight, WC waist circumference, ∆BW annual weight change, ∆WC annual WC change.
  2. 1DCH: n = 2,165 on baseline WC, n = 2,130 on follow-up WC and n = 2,128 on ∆WC. INTER99: n = 4,067 on baseline WC, n = 3,540 on follow-up WC and n = 3,536 on ∆WC.
  3. 2Sum of BMI, WC or WHR associated risk-alleles. In MONICA information was available in n = 989 on BMI SNP-score, n = 1,250 on WC SNP-score, n = 1,185 on WHR SNP-score and n = 878 on complete SNP-score. In DCH n = 1,438 on BMI SNP-score, n = 1,805 on WC SNP-score, n = 1,624 on WHR SNP-score and n = 1,247 on complete SNP-score. In INTER99 n = 2,511 on BMI SNP-score, n = 3,381 on WC SNP-score, n = 3,264 on WHR SNP-score, n = 2,082 on complete score.
  4. Results presented as median (5–95 percentiles) unless otherwise stated.