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Table 3 Relationship between changes in plasma apolipoprotein A-V levels and metabolic parameters

From: Effects of a 3-year dietary intervention on age-related changes in triglyceride and apolipoprotein A-V levels in patients with impaired fasting glucose or new-onset type 2 diabetes as a function of the APOA5 -1131 T > C polymorphism

  Changed apo A-V levels
All subjects TT allele C allele (TC and CC)
r 1 p 1 r 2 p 2 r 3 p 3 r 1 p 1 r 2 p 2 r 3 p 3 r 1 p 1 r 2 p 2 r 3 p 3
Baseline levels                   
  Triglyceride −0.018 0.809 - - - - −0.082 0.456 - - - - 0.052 0.608 - - - -
  Apo A-V −0.543 <0.001 −0.555 <0.001 - - −0.535 <0.001 −0.552 <0.001 - - −0.613 <0.001 −0.617 <0.001 - -
  Free fatty acids −0.159 0.030 −0.158 0.031 −0.047 0.529 −0.086 0.439 −0.066 0.554 −0.050 0.656 −0.237 0.017 −0.233 0.020 −0.036 0.722
  HDL cholesterol −0.203 0.005 −0.221 0.002 −0.105 0.153 −0.156 0.156 −0.173 0.118 −0.111 0.323 −0.263 0.008 −0.266 0.008 −0.107 0.295
Changed levels                   
  Free fatty acids 0.275 <0.001 0.275 <0.001 0.247 0.001 0.231 0.035 0.226 0.040 0.292 0.008 0.304 0.002 0.301 0.002 0.190 0.060
  Triglycerides 0.022 0.767 0.019 0.800 −0.084 0.257 −0.166 0.131 −0.195 0.077 −0.299 0.006 0.207 0.038 0.221 0.028 0.151 0.138
  HDL cholesterol 0.366 <0.001 0.365 <0.001 0.354 <0.001 0.411 <0.001 0.405 <0.001 0.412 <0.001 0.313 0.002 0.310 0.002 0.266 0.008
  1. Log-transformed.
  2. Tested by Partial correlation analysis.
  3. r 1 : correlation coefficient after adjusting for age, sex, and changes in body weight.
  4. r 2 : correlation coefficient after adjusting for age, sex, changes in body weight and initial triglyceride levels.
  5. r 3 : correlation coefficient after adjusting for age, sex, changes in body weight, initial triglyceride levels, and initial apo A-V levels.