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Table 2 Summary of the secondary outcomes implemented in Executive B across all time points

From: Reducing occupational stress with a B-vitamin focussed intervention: a randomized clinical trial: study protocol

  Visit 1 (baseline) Visit 2 (6 months)
Screening Medical history (ie demographic screen, medication use) Medical history (ie medication use)
Biochemical MBA & CRP MBA & CRP
Homocysteine Homocysteine
B Vitamins (B6, B12) B Vitamins (B6, B12)
Folate Folate
COMT COMT
SLC6A4 SLC6A4
FKBP5 FKBP5
NPY NPY
ADCYAP1R1 ADCYAP1R1
MTHFR MTHFR
CPS1 CPS1
CBS and DPEP1 CBS and DPEP1
Health FFQ FFQ
BDI-II BDI-II
POMS POMS
GHQ GHQ
PSS PSS
Cardiovascular Brachial BP Brachial BP
Aortic BP Aortic BP
Carotid-femoral PWV Carotid-femoral PWV
Neuroimaging Structural MRI Structural MRI
Default mode network activation Default mode network activation
Metabolite scan (MRS) Metabolite scan (MRS)
N-Back working memory (functional MRI) N-Back working memory (functional MRI)
Other NEO PI-R Estimate of compliance
WASI  
  1. COMT = Catechol-O-methyltransferase gene, SLC6A4 = Serotonin-transporter gene-linked polymorphic region, FKBP5 = Glucocorticoid receptor-regulating co-chaperone of stress proteins, NPY = Neuropeptide Y, ADCYAP1R1 = Pituitary adenylate cyclase-activating polypeptide receptor, MTHFR = Methylenetetrahydrofolate reductase, CPSI = Carbamoyl phosphate synthetase 1, CBS and DPEP1 = Cystathionine –β-synthase and Dipeptidase 1, FFQ = Food Frequency Questionnaire, BDI-II = Beck Depression Inventory II, POMS = Profile of Mood States, GHQ = General Health Questionnaire, PSS = Perceived Stress Scale, NEO PI-R = NEO-Personality Inventory Revised, WASI = Wechsler Abbreviated Scale of Intelligence.