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Table 4 Laboratory parameters in MetS patients at baseline and post-fasting in two groups a

From: L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study

 

Control group

Carnitine group

Δ P-value

 

Baseline

Post-fasting

P-valueb

Change

Baseline

Post-fasting

P-valueb

Change

FBG (mmol/L)

5.1 ± 0.92

3.8 ± 0.86

0.007

-1.3 ± 0.93

5.2 ± 0.61

4.2 ± 0.66

0.001

-1.07 ± 0.76

0.066

FINS (µU/mL)

16.64 ± 4.98

10.32 ± 5.44

<0.001

-6.32 ± 3.44

17.87 ± 5.81

8.30 ± 4.05

<0.001

-9.9 ± 3.58

0.046

HOMA-IR

3.77 ± 1.35

1.74 ± 0.98

<0.001

-2.03 ± 1.33

4.13 ± 1.38

1.55 ± 0.87

<0.001

-2.78 ± 1.07

0.078

HS-CRP (mg/L)

2.3 ± 3.74

2.2 ± 3.22

0.716

-0.04 ± 0.38

3.06 ± 1.69

2.7 ± 1.45

0.794

-0.09 ± 1.64

0.991

UA (umol/L)

322.2 ± 93.92

527.6 ± 175.1

<0.001

205.4 ± 167

329.3 ± 101.82

460.16 ± 161.33

0.003

130.8 ± 132.9

0.196

FFA (umol/L)

444.4 ± 120.3

990 ± 469.5

0.004

545.6 ± 450.3

454.0 ± 181.51

1187.9 ± 490.96

0.002

831.1 ± 573.9

0.076

AST (U/L)

22.2 ± 5.87

30.6 ± 15.7

0.014

8.39 ± 11.63

26.1 ± 7.74

33.9 ± 17.01

0.045

7.71 ± 12.99

0.883

ALT (U/L)

21.3 ± 11.98

31.3 ± 26.31

0.030

9.99 ± 15.96

25.7 ± 10.76

29.3 ± 14.13

0.112

5.5 ± 12.08

0.403

γ-GGT (U/L)

24.7 ± 10.7

22.3 ± 9.32

0.076

-2.07 ± 4.18

30.2 ± 13.97

22.6 ± 8.62

0.002

-7.07 ± 6.82

0.024

  1. Abbreviation: γ-GGT γ-glutamyltransferase, AST Aspartate aminotransferase, ALT Alanine aminotransferase, FBP Fasting blood glucose, FINS Fasting insulin, HOMA-IR Homeostasis model assessment- Insulin Resistance, Hs-CRP Hypersensitivity C reaction protein, FFA free fatty acid, UA uric acid.
  2. aVariables are expressed as mean ± SD.
  3. b P-value was determined by paired test between baseline and post-fasting.
  4. Δ P-value was determined by unpaired test between groups in difference.
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Nutrition Journal

ISSN: 1475-2891

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