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Table 4 Laboratory parameters in MetS patients at baseline and post-fasting in two groups a

From: L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study

  Control group Carnitine group Δ P-value
  Baseline Post-fasting P-valueb Change Baseline Post-fasting P-valueb Change
FBG (mmol/L) 5.1 ± 0.92 3.8 ± 0.86 0.007 -1.3 ± 0.93 5.2 ± 0.61 4.2 ± 0.66 0.001 -1.07 ± 0.76 0.066
FINS (µU/mL) 16.64 ± 4.98 10.32 ± 5.44 <0.001 -6.32 ± 3.44 17.87 ± 5.81 8.30 ± 4.05 <0.001 -9.9 ± 3.58 0.046
HOMA-IR 3.77 ± 1.35 1.74 ± 0.98 <0.001 -2.03 ± 1.33 4.13 ± 1.38 1.55 ± 0.87 <0.001 -2.78 ± 1.07 0.078
HS-CRP (mg/L) 2.3 ± 3.74 2.2 ± 3.22 0.716 -0.04 ± 0.38 3.06 ± 1.69 2.7 ± 1.45 0.794 -0.09 ± 1.64 0.991
UA (umol/L) 322.2 ± 93.92 527.6 ± 175.1 <0.001 205.4 ± 167 329.3 ± 101.82 460.16 ± 161.33 0.003 130.8 ± 132.9 0.196
FFA (umol/L) 444.4 ± 120.3 990 ± 469.5 0.004 545.6 ± 450.3 454.0 ± 181.51 1187.9 ± 490.96 0.002 831.1 ± 573.9 0.076
AST (U/L) 22.2 ± 5.87 30.6 ± 15.7 0.014 8.39 ± 11.63 26.1 ± 7.74 33.9 ± 17.01 0.045 7.71 ± 12.99 0.883
ALT (U/L) 21.3 ± 11.98 31.3 ± 26.31 0.030 9.99 ± 15.96 25.7 ± 10.76 29.3 ± 14.13 0.112 5.5 ± 12.08 0.403
γ-GGT (U/L) 24.7 ± 10.7 22.3 ± 9.32 0.076 -2.07 ± 4.18 30.2 ± 13.97 22.6 ± 8.62 0.002 -7.07 ± 6.82 0.024
  1. Abbreviation: γ-GGT γ-glutamyltransferase, AST Aspartate aminotransferase, ALT Alanine aminotransferase, FBP Fasting blood glucose, FINS Fasting insulin, HOMA-IR Homeostasis model assessment- Insulin Resistance, Hs-CRP Hypersensitivity C reaction protein, FFA free fatty acid, UA uric acid.
  2. aVariables are expressed as mean ± SD.
  3. b P-value was determined by paired test between baseline and post-fasting.
  4. Δ P-value was determined by unpaired test between groups in difference.