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Table 3 Mean values of all variables by VDR genotype in subjects without MetSyn

From: Relationship between Vitamin D Receptor gene polymorphisms and the components of metabolic syndrome

Variables

VDR 2228570 C > T (Fok I)

p

VDR 1544410 A > G (Bsm I)

p

 

FF

Ff

ff

 

BB

Bb

bb

 
 

n = 130

n = 91

n = 22

 

n = 109

n = 102

n = 32

 

WC (cm)

89 (±10)

95 (±16)

90 (±9)

0.086

93 (±14)

93 (±13)

86 (±11)

0.293

Triglycerides (mg/dl)

90 (±28)

117 (±54)‡

134 (±80)

0.005

107 (±46)

113 (±58)

100 (±45)

0.696

BPS (mmHg)

122 (±17)

121 (±21)

124 (±14)

0.923

119 (±21)

125 (±16)

121 (±21)

0.194

BPD (mmHg)

75 (±10)

76 (±14)

79 (±10)

0.316

75 (±13)

77 (±11)

74 (±14)

0.556

Fasting glucose (mg/dl)

92 (±10)

92 (±11)

89 (±10)

0.607

92 (±11)

90 (±9)

93 (±8)

0.588

HDL cholesterol (mg/dl)

50 (±11)

45 (±12)‡

42 (±11)

0.031

47 (±13)

47 (±11)

42 (±6)

0.253

Homa IR

1.6 (±1.4)

1.7 (±1.4)

1.0 (±0.4)

0.398

1.7 (±1.7)

1.6 (±0.9)

1.2 (±0.7)

0.749

Homa β

92 (±62)

103 (±80)

87 (±93)

0.711

96 (±81)

107 (±71)

70 (±46)

0.424

25(OH)D3 (ng/ml)

20 (±6)

22 (±6.4)

24.4 (±5)

0.062

20.8 (±6)

23 (±6.4)

18 (±7.2)†

0.023

iPTH (pg/dl)

41 (±24)

36 (±18)

38 (±11)

0.019

40 (±20)

37 (±20)

32 (±24)

0.361

  1. Legend: WC, Waist circumference; BPS, Systolic blood pressure; BPD, Diastolic blood pressure; HOMA IR, Insulin resistance; HOMA β, Cell function; iPTH, Intact parathyroid hormone; 25(OH)D3, Vitamin D. Data are expressed as mean (Standard Deviation). P values were calculated using ANOVA followed by Bonferroni test and adjusted for age. † significant for the heterozygous genotype; ‡ significant for the normal dominant homozygous genotype.