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Table 2 Mean values of all variables by VDR genotype in subjects with MetSyn

From: Relationship between Vitamin D Receptor gene polymorphisms and the components of metabolic syndrome

Variables

VDR 2228570 C > T (Fok I)

p

VDR 1544410 A > G (Bsm I)

p

 

FF

Ff

ff

 

BB

Bb

bb

 
 

n = 130

n = 91

n = 22

 

n = 109

n = 102

n = 32

 

WC (cm)

103 (±13)

103 (±12)

106 (±13)

0.433

104 (±13)

103 (±13)

104 (±13)

0.863

Triglycerides (mg/dl)

155 (±59)

174 (±81)

163 (±103)

0.204

151 (±59)

173 (±87)

163 (±64)

0.523

BPS (mmHg)

140 (±18)

137 (±16)

147 (±24)

0.377

139 (±14)

139 (±20)

134 (±20)

0.490

BPD (mmHg)

84 (±12)

82 (±10)

85 (±12)

0.726

84 (±10)

83 (±10)

82 (±8)

0.822

Fasting glucose (mg/dl)

99 (±10)

98 (±13)

99 (±14)

0.707

100 (±12)

97 (±13)

99 (±12)

0.404

HDL cholesterol (mg/dl)

43 (±12)

40 (±9)

40 (±12)

0.306

43 (±12)

42 (±10)

40 (±12)

0.231

HOMA IR

2 (±2)

3 (±2)

4 (±3)†

0.014

3 (±1)

3 (±2)

4 (±3)

0.259

HOMA β

100 (±77)

159 (±137)‡

145 (±61)

0.010

123 (±77)

142 (±137)

137 (±107)

0.729

25(OH)D3 (ng/ml)

24 (±6.8)

24.8 (±16.8)

24 (±8)

0.828

24 (±6.4)

62 (±8.4)

24 (±8)

0.389

iPTH (pg/dl)

37 (±19)

49 (±22)‡

42 (±25)

0.022

44 (±15)

49 (±22)

46 (±25)

0.649

  1. Legend: WC, Waist circumference; BPS, Systolic blood pressure; BPD, Diastolic blood pressure; HOMA IR, Insulin resistance; HOMA β, Cell function; iPTH, Intact parathyroid hormone; 25(OH)D 3 , Vitamin D. Data are expressed as mean (Standard Deviation). P values were calculated using ANOVA followed by Bonferroni test and adjusted for age. † significant for the heterozygous genotype; ‡ significant for the normal dominant homozygous genotype.