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Table 2 Effect of fish oil supplementation on plasma and red blood cell phospholipid fatty acids*

From: A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population

Markers Placebo Omega-3 Treatment difference S.E. of difference P-value of difference
Before After Before After
Plasma PL% EPA 0.332 0.400 0.329 1.225 +0.832 0.170 p < 0.001
Plasma PL% DHA 1.623 1.370 1.618 2.157 +0.762 0.281 p = 0.008
Plasma PL% EPA&DHA 1.95 1.77 1.95 3.38 +1.61 0.408 p < 0.001
RBC% EPA 0.314 0.373 0.366 1.026 +0.606 0.108 p < 0.001
RBC% DHA 2.930 3.082 3.169 4.169 +0.708 0.245 p = 0.019
RBC% EPA&DHA 3.244 3.455 3.535 5.195 +1.314 0.298 p = 0.002
  1. * Repeated measure general linear models. PL = phospholipid, EPA = eicosapentaenoic acid, DHA = docosahexaenoic acid.