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Table 2 Repeated-measures analysis of variance assessments at baseline and after 3 and 6 months in fluoxetine + vitamin C and fluoxetine + placebo groups

From: Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study

  Group effect Time effect Interaction
Variable F Df P F Df P F Df P
CDRS 155.90 1, 11 <0.0001 294.59 1.6, 17 <0.0001 25.14 1.4, 18.4 <0.0001
CDI 89.69 1, 11 <0.0001 512.77 1.8, 19.4 <0.0001 57.21 1.8, 19.8 <0.0001
CGI 0.000 1, 11 1.000 447.95 1.6, 17.2 <0.0001 0.68 1.1, 12.1 0.438
  1. Statistical significance defined as P<0.05. CDI: Children’s Depression Inventory; CDRS: Children’s Depression Rating Scale; CGI: Clinical Global Impression.