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Table 2 Presenting symptoms of all 124 eligible children

From: Double-blind placebo-controlled food challenges in children with alleged cow’s milk allergy: prevention of unnecessary elimination diets and determination of eliciting doses

Symptom

Number of patients (%)

Gastrointestinal tract

 
 

Vomiting

30 (24.2%)

 

Diarrhea

17 (13.7%)

 

Constipation

14 (11.3%)

 

Colic

24 (19.4%)

 

Bloody stool

17 (13.7%)

 

Abdominal pain

3 (2.4%)

 

Feeding problems

15 (12.1%)

Respiratory tract

 
 

Dyspnea and wheezing

13 (10.5%)

Skin manifestations

 
 

Eczema

50 (40.3%)

 

Swelling

5 (4.0%)

 

Urticaria

3 (2.4%)

 

Erythematous exanthema

10 (8.1%)

Other

 
 

Excessive crying

59 (47.6%)

 

Positive family history

8 (6.5%)*

  1. Feeding problems were significantly more often present in the DBPCFC-negative group (p=0.046).
  2. ‡ Swelling was significantly more often present in the DBPCFC-positive group (p=0.023).
  3. *In these 8 children the positive family history was one of the reasons for performing the double-blind placebo-controlled food challenge. In total 65 children (52.4%) had a positive family history.