Skip to main content

Table 2 Presenting symptoms of all 124 eligible children

From: Double-blind placebo-controlled food challenges in children with alleged cow’s milk allergy: prevention of unnecessary elimination diets and determination of eliciting doses

Symptom Number of patients (%)
Gastrointestinal tract  
  Vomiting 30 (24.2%)
  Diarrhea 17 (13.7%)
  Constipation 14 (11.3%)
  Colic 24 (19.4%)
  Bloody stool 17 (13.7%)
  Abdominal pain 3 (2.4%)
  Feeding problems 15 (12.1%)
Respiratory tract  
  Dyspnea and wheezing 13 (10.5%)
Skin manifestations  
  Eczema 50 (40.3%)
  Swelling 5 (4.0%)
  Urticaria 3 (2.4%)
  Erythematous exanthema 10 (8.1%)
Other  
  Excessive crying 59 (47.6%)
  Positive family history 8 (6.5%)*
  1. Feeding problems were significantly more often present in the DBPCFC-negative group (p=0.046).
  2. ‡ Swelling was significantly more often present in the DBPCFC-positive group (p=0.023).
  3. *In these 8 children the positive family history was one of the reasons for performing the double-blind placebo-controlled food challenge. In total 65 children (52.4%) had a positive family history.