Figure 2

Cumulative MEDs for an acute allergic reaction to cow's milk protein in the JBH population compared to various CMA studies. Cumulative probability distribution based on individual MEDs for cow’s milk (expressed as CMP) for cow’s milk allergic children of the Jeroen Bosch Hospital and for populations from the literature [5, 22–24]. 100 mg CMP corresponds with 5,6 ml of our test feeding. Two distributions were compiled for the JBH population. JBH_children is the patient selection of DBPCFC-positive children older than 12 months. JBH_infants consists of DBPCFC-positive children aged 0 – 12 months. See also Table 5. CMA, cow’s milk allergy; CMP, cow’s milk protein; JBH, Jeroen Bosch Hospital; MED, minimum eliciting dose. ▲ JBH_children; ■ JBH_infants; □ Flinterman et al. (2006); ▬ Baehler et al. (1996); ♦ Caminiti et al. (2009); ○ Patriarca et al. (2002).