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Table 1 Basic characteristics of 2108 elderly Japanese women categorized with and without frailty

From: High protein intake is associated with low prevalence of frailty among old Japanese women: a multicenter cross-sectional study

 

Total (n = 2108)

No frailty* (n = 1627)

Frailty* (n = 481)

P

Mean ± SD or n (%)

Frailty status*, n (%)

    

   No frailty

1627 (77.2)

-

-

-

   Frailty

481 (22.8)

-

-

-

Frailty criteria, n (%)

    

   Slowness and weakness

710 (33.7)

234 (14.4)

476 (99.0)

-

   Exhaustion

540 (25.6)

205 (12.6)

335 (69.8)

-

   Low physical activity

528 (25.1)

228 (14.0)

300 (62.4)

-

   Unintentional weight loss

112 (5.3)

50 (3.1)

62 (12.9)

-

Age, years

74.7 ± 5.0

73.9 ± 4.6

77.3 ± 5.3

<0.0001

Body height, cm

150.4 ± 5.5

150.7 ± 5.2

149.1 ± 6.1

<0.0001

Body weight, kg

51.4 ± 7.8

51.4 ± 7.4

51.5 ± 9.2

0.96

Body mass index, kg/m2

22.7 ± 3.2

22.6 ± 3.0

23.1 ± 3.6

<0.0001

Survey year, n (%)

   

0.27

   2011

1342 (63.7)

1046 (64.3)

296 (61.5)

 

   2012

766 (36.3)

581 (35.7)

185 (38.5)

 

Residential block, n (%)

   

0.38

   Hokkaido and Tohoku

193 (9.2)

142 (8.7)

51 (10.6)

 

   Kanto

526 (25.0)

404 (24.8)

122 (25.4)

 

   Hokuriku and Tokai

510 (24.2)

410 (25.2)

100 (20.8)

 

   Kinki

262 (12.4)

199 (12.2)

63 (13.1)

 

   Chugoku and Shikoku

342 (16.2)

265 (16.3)

77 (16.0)

 

   Kyushu

275 (13.1)

207 (12.7)

68 (14.1)

 

Size of residential area, n (%)

   

0.26

   City with a population ≥1 million

274 (13.0)

204 (12.5)

70 (14.6)

 

   City with a population <1 million

1598 (75.8)

1247 (76.6)

351 (73.0)

 

   Town and village

236 (11.2)

176 (10.8)

60 (12.5)

 

Living alone, n (%)

   

0.30

   No

1759 (83.4)

1365 (83.9)

394 (81.9)

 

   Yes

349 (16.6)

262 (16.1)

87 (18.1)

 

Marital status, n (%)

   

<0.0001

   Single

4 (0.2)

3 (0.2)

1 (0.2)

 

   Married

1275 (60.5)

1035 (63.6)

240 (49.9)

 

   Widowed

777 (36.9)

546 (33.6)

231 (48.0)

 

   Separated

52 (2.5)

43 (2.6)

9 (1.9)

 

Education, n (%)

   

0.04

   ≤Junior high school and others

977 (46.4)

732 (45.0)

245 (50.9)

 

   High school

933 (44.3)

733 (45.1)

200 (41.6)

 

   ≥Some college

198 (9.4)

162 (10.0)

36 (7.5)

 

Current smoking, n (%)

   

0.002

   No

2054 (97.4)

1595 (98.0)

459 (95.4)

 

   Yes

54 (2.6)

32 (2.0)

22 (4.6)

 

Alcohol drinking, n (%)

   

<0.0001

   No

1695 (80.4)

1278 (78.6)

417 (86.7)

 

   Yes

413 (19.6)

349 (21.5)

64 (13.3)

 

Dietary supplement use, n (%)

   

0.0002

   No

1475 (70.0)

1106 (68.0)

369 (76.7)

 

   Yes

633 (30.0)

521 (32.0)

112 (23.3)

 

Physical activity, total metabolic equivalents-hours/d

39.0 ± 6.6

40.4 ± 6.3

34.4 ± 5.2

<0.0001

History of chronic disease‡, n (%)

   

<0.0001

   No

1059 (50.2)

864 (53.1)

195 (40.5)

 

   Yes

1049 (49.8)

763 (46.9)

286 (59.5)

 

Depression symptoms§, n (%)

   

<0.0001

   No

1617 (76.7)

1363 (83.8)

254 (52.8)

 

   Yes

491 (23.3)

264 (16.2)

227 (47.2)

 

Energy intake, kcal/d

1737 ± 475

1767 ± 473

1636 ± 465

<0.0001

Macronutrient intake||

    

   Total protein, g/d

74.0 ± 14.3

74.6 ± 14.5

72.0 ± 13.2

0.0003

   Animal protein¶, g/d

43.5 ± 15.5

44.0 ± 15.6

41.9 ± 14.9

0.009

   Plant protein**, g/d

30.5 ± 4.4

30.6 ± 4.4

30.1 ± 4.6

0.03

   Fat, g/d

50.1 ± 9.6

50.3 ± 9.7

49.3 ± 9.2

0.04

   Carbohydrate, g/d

241 ± 32

240 ± 32

245 ± 30

0.005

Amino acid intake||

    

   Essential amino acids, g/d

28.8 ± 6.16

29.0 ± 6.25

28.1 ± 5.77

0.001

   Branched chain amino acids, g/d

12.5 ± 2.49

12.6 ± 2.54

12.2 ± 2.32

0.001

   Leucine, g/d

5.64 ± 1.12

5.68 ± 1.14

5.50 ± 1.04

0.001

   Isoleucine, g/d

3.17 ± 0.65

3.19 ± 0.66

3.08 ± 0.61

0.001

   Valine, g/d

3.72 ± 0.72

3.75 ± 0.74

3.63 ± 0.67

0.001

   Sulfur amino acids, g/d

2.83 ± 0.55

2.85 ± 0.56

2.77 ± 0.51

0.003

   Methionine, g/d

1.76 ± 0.40

1.77 ± 0.40

1.71 ± 0.38

0.01

   Cysteine, g/d

1.08 ± 0.15

1.09 ± 0.16

1.07 ± 0.14

0.0007

  1. SD, standard deviation.
  2. *Frailty score (0-5) was defined as the sum of poor physical function (two points), exhaustion (one point), low physical activity (one point), and unintentional weight loss (one point). A score of ≥3 was classified as indicating frailty.
  3. †Means for continuous values were compared by Student’s t test and proportions for categorical values were compared by the chi-square test.
  4. ‡History of chronic disease was defined as having had any of the following self-reported diseases: stroke, myocardial infarction, hypertension, diabetes, or chronic rheumatism.
  5. §Depression symptoms were defined as a Center for Epidemiologic Studies Depression score ≥16.
  6. ||Nutrient intakes were energy-adjusted according to the residual method.
  7. ¶Protein from the following four food groups were included in animal protein: fish and shellfish, meat, eggs, and dairy products.
  8. **Protein from the following eight food groups were included in plant protein: cereals, pulses, potatoes, confectionaries, fruits, vegetables, alcoholic beverages, and non-alcoholic beverages.